SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RI4_A_SAMA299_0
(MRNA CAPPING ENZYME)		 4n72 PYRUVATE
DEHYDROGENASE
(DIHYDROLIPOYLTRANSA
CETYLASE COMPONENT)
(Escherichia
coli) 		5 / 12 GLY A 545
GLY A 496
ILE A 493
TYR A 492
GLN A 543
 None
 1.13A 1ri4A-4n72A:
undetectable		 1ri4A-4n72A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4n72 PYRUVATE
DEHYDROGENASE
(DIHYDROLIPOYLTRANSA
CETYLASE COMPONENT)
(Escherichia
coli) 		4 / 6 ARG A 440
ILE A 462
VAL A 574
LEU A 594
 None
 1.07A 4em2A-4n72A:
undetectable		 4em2A-4n72A:
18.78