SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n7b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 4 ARG A 202
ALA A 205
ALA A 296
GLU A 298
 None
 1.12A 1e7bB-4n7bA:
undetectable		 1e7bB-4n7bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 8 GLN A 253
LEU A 281
TYR A 288
LEU A 215
 None
 0.91A 1hk2A-4n7bA:
undetectable		 1hk2A-4n7bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 8 GLN A 253
LEU A 281
TYR A 288
LEU A 215
 None
 0.95A 1hk3A-4n7bA:
undetectable		 1hk3A-4n7bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 8 HIS A 126
VAL A 129
LEU A 168
THR A 167
 SO4  A 402 (-4.1A)
None
None
SO4  A 402 (-3.4A)
 0.84A 2it4A-4n7bA:
undetectable		 2it4A-4n7bA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4n7b LYTB
(Plasmodium
falciparum) 		3 / 3 THR A 200
SER A 194
LYS A 103
 None
None
NA  A 405 ( 4.6A)
 0.86A 3aocC-4n7bA:
undetectable		 3aocC-4n7bA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4n7b LYTB
(Plasmodium
falciparum) 		5 / 10 HIS A  76
HIS A 126
HIS A  43
VAL A  42
THR A 167
 SO4  A 402 (-4.4A)
SO4  A 402 (-4.1A)
SO4  A 402 (-3.9A)
None
SO4  A 402 (-3.4A)
 1.32A 3dazA-4n7bA:
undetectable		 3dazA-4n7bA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 4n7b LYTB
(Plasmodium
falciparum) 		5 / 10 HIS A  76
HIS A 126
HIS A  43
VAL A  42
THR A 167
 SO4  A 402 (-4.4A)
SO4  A 402 (-4.1A)
SO4  A 402 (-3.9A)
None
SO4  A 402 (-3.4A)
 1.33A 3dcsA-4n7bA:
undetectable		 3dcsA-4n7bA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 4 VAL A 129
GLU A 128
GLY A 122
LEU A 120
 None
 1.07A 5g5gC-4n7bA:
undetectable		 5g5gC-4n7bA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 4n7b LYTB
(Plasmodium
falciparum) 		5 / 10 HIS A  76
HIS A 126
HIS A  43
VAL A  42
THR A 167
 SO4  A 402 (-4.4A)
SO4  A 402 (-4.1A)
SO4  A 402 (-3.9A)
None
SO4  A 402 (-3.4A)
 1.40A 5jncB-4n7bA:
undetectable		 5jncB-4n7bA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 4n7b LYTB
(Plasmodium
falciparum) 		5 / 10 HIS A  76
HIS A 126
HIS A  43
VAL A  42
THR A 167
 SO4  A 402 (-4.4A)
SO4  A 402 (-4.1A)
SO4  A 402 (-3.9A)
None
SO4  A 402 (-3.4A)
 1.38A 5ku6B-4n7bA:
undetectable		 5ku6B-4n7bA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 6 HIS A 126
VAL A 129
LEU A 168
THR A 167
 SO4  A 402 (-4.1A)
None
None
SO4  A 402 (-3.4A)
 0.86A 5ogjA-4n7bA:
undetectable		 5ogjA-4n7bA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 6 HIS A 126
VAL A 129
LEU A 168
THR A 167
 SO4  A 402 (-4.1A)
None
None
SO4  A 402 (-3.4A)
 0.86A 5ogjB-4n7bA:
undetectable		 5ogjB-4n7bA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 5 HIS A 126
VAL A 129
LEU A 168
THR A 167
 SO4  A 402 (-4.1A)
None
None
SO4  A 402 (-3.4A)
 0.85A 5ohhA-4n7bA:
undetectable		 5ohhA-4n7bA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 4n7b LYTB
(Plasmodium
falciparum) 		4 / 6 HIS A 126
VAL A 129
LEU A 168
THR A 167
 SO4  A 402 (-4.1A)
None
None
SO4  A 402 (-3.4A)
 0.86A 5ohhB-4n7bA:
undetectable		 5ohhB-4n7bA:
19.22