SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n7c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_A_LDPA501_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 4n7c BLA G 4 ALLERGEN
VARIANT 1
(Blattella
germanica) 		4 / 7 GLY A 111
PHE A  81
ILE A  83
PHE A  49
 None
 1.01A 2qmzA-4n7cA:
undetectable
2qmzB-4n7cA:
undetectable		 2qmzA-4n7cA:
24.03
2qmzB-4n7cA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 4n7c BLA G 4 ALLERGEN
VARIANT 1
(Blattella
germanica) 		5 / 12 ALA A 107
PHE A  49
ARG A  26
ILE A  46
THR A 101
 None
 0.95A 2w3bA-4n7cA:
undetectable		 2w3bA-4n7cA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4n7c BLA G 4 ALLERGEN
VARIANT 1
(Blattella
germanica) 		4 / 7 GLY A 111
PHE A  81
ILE A  83
PHE A  49
 None
 0.87A 4fglC-4n7cA:
undetectable		 4fglC-4n7cA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_B_ML1B302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4n7c BLA G 4 ALLERGEN
VARIANT 1
(Blattella
germanica) 		4 / 6 GLY A 111
PHE A  81
ILE A  83
PHE A  49
 None
 0.94A 4qogA-4n7cA:
undetectable
4qogB-4n7cA:
undetectable		 4qogA-4n7cA:
24.03
4qogB-4n7cA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4n7c BLA G 4 ALLERGEN
VARIANT 1
(Blattella
germanica) 		3 / 3 LEU A 147
TYR A 168
SER A 173
 None
 0.76A 5iktA-4n7cA:
undetectable		 5iktA-4n7cA:
15.81