SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 298
HIS A 303
HIS A 340
HIS A 351
 MN  A 502 (-2.2A)
MN  A 502 (-3.3A)
MN  A 501 (-3.2A)
MN  A 502 (-3.2A)
 0.51A 1ei6A-4n7tA:
13.9		 1ei6A-4n7tA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 8 ASP A  13
ASP A 298
HIS A 303
HIS A 340
HIS A 351
 MN  A 501 (-2.0A)
MN  A 502 (-2.2A)
MN  A 502 (-3.3A)
MN  A 501 (-3.2A)
MN  A 502 (-3.2A)
 0.54A 1ei6C-4n7tA:
14.0		 1ei6C-4n7tA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 GLN A 169
ALA A 171
PHE A 115
ARG A 190
 SO4  A 503 (-3.0A)
None
None
None
 1.27A 1t9wA-4n7tA:
undetectable		 1t9wA-4n7tA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 8 ARG A 129
ASN A 220
HIS A 222
ARG A 184
 None
 1.34A 1u1jA-4n7tA:
undetectable		 1u1jA-4n7tA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 PHE A 285
ARG A   6
HIS A   8
VAL A 247
 None
 1.32A 1wu8A-4n7tA:
1.7
1wu8C-4n7tA:
1.2		 1wu8A-4n7tA:
20.53
1wu8C-4n7tA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 THR A  81
PRO A 357
PRO A  62
 None
None
GOL  A 505 (-4.8A)
 0.76A 2d55C-4n7tA:
undetectable		 2d55C-4n7tA:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 PRO A  62
THR A  81
PRO A 357
 GOL  A 505 (-4.8A)
None
None
 0.83A 2d55C-4n7tA:
undetectable		 2d55C-4n7tA:
3.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ILE A 325
PRO A 322
PHE A 317
ILE A 336
 None
 1.16A 2hjhA-4n7tA:
undetectable		 2hjhA-4n7tA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 12 ILE A 253
GLY A  95
HIS A 351
ASP A 298
ASP A  13
 TPO  A  92 ( 4.7A)
TPO  A  92 ( 3.9A)
MN  A 502 (-3.2A)
MN  A 502 (-2.2A)
MN  A 501 (-2.0A)
 1.24A 2pgfA-4n7tA:
undetectable		 2pgfA-4n7tA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 12 GLY A 341
GLY A  16
GLU A 354
ASN A  28
PHE A 297
 None
 1.16A 2vdvE-4n7tA:
undetectable		 2vdvE-4n7tA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 11 GLY A 341
GLY A  16
GLU A 354
ASN A  28
PHE A 297
 None
 1.16A 2vdvF-4n7tA:
undetectable		 2vdvF-4n7tA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 6 LEU A 276
ILE A 277
MET A 328
VAL A  70
 None
 1.15A 2ygoA-4n7tA:
undetectable		 2ygoA-4n7tA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 VAL A  70
ASP A 318
LEU A  48
ILE A  61
 None
 1.05A 3avpA-4n7tA:
undetectable		 3avpA-4n7tA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 SER A 140
GLY A 141
THR A 142
 None
SO4  A 503 (-3.2A)
None
 0.20A 3k9wA-4n7tA:
undetectable		 3k9wA-4n7tA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASN A 266
ASP A  13
GLU A  85
THR A  94
 None
MN  A 501 (-2.0A)
None
None
 1.39A 3p2kC-4n7tA:
undetectable		 3p2kC-4n7tA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASN A 386
ASP A 332
THR A 279
SER A   2
 None
 1.43A 3p2kC-4n7tA:
undetectable		 3p2kC-4n7tA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 ILE A 325
LEU A 321
THR A  77
ILE A  56
 None
 0.98A 3p50A-4n7tA:
undetectable		 3p50A-4n7tA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 ILE A 325
LEU A 321
THR A  77
ILE A  56
 None
 0.98A 3p50B-4n7tA:
undetectable		 3p50B-4n7tA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 ASN A 136
ALA A 135
LYS A 137
 None
 0.96A 3runA-4n7tA:
undetectable		 3runA-4n7tA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 LEU A  48
PRO A  71
VAL A  70
ASP A 318
 None
 1.18A 3ufnA-4n7tA:
undetectable
3ufnB-4n7tA:
undetectable		 3ufnA-4n7tA:
15.59
3ufnB-4n7tA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 262
VAL A 247
GLY A 248
ASP A 252
 None
 1.49A 3w9tA-4n7tA:
undetectable		 3w9tA-4n7tA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 262
VAL A 247
GLY A 248
ASP A 252
 None
 1.48A 3w9tB-4n7tA:
undetectable		 3w9tB-4n7tA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 262
VAL A 247
GLY A 248
ASP A 252
 None
 1.49A 3w9tC-4n7tA:
undetectable		 3w9tC-4n7tA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 262
VAL A 247
GLY A 248
ASP A 252
 None
 1.48A 3w9tD-4n7tA:
undetectable		 3w9tD-4n7tA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 262
VAL A 247
GLY A 248
ASP A 252
 None
 1.48A 3w9tE-4n7tA:
undetectable		 3w9tE-4n7tA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 262
VAL A 247
GLY A 248
ASP A 252
 None
 1.49A 3w9tF-4n7tA:
undetectable		 3w9tF-4n7tA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 ASP A 262
VAL A 247
GLY A 248
ASP A 252
 None
 1.48A 3w9tG-4n7tA:
undetectable		 3w9tG-4n7tA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G5J_A_0WMA1102_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 PHE A 215
TYR A 208
HIS A 173
ILE A 177
 None
 1.04A 4g5jA-4n7tA:
undetectable		 4g5jA-4n7tA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 ILE A 259
LEU A 234
ALA A 246
VAL A 247
 None
 0.82A 4g77A-4n7tA:
undetectable		 4g77A-4n7tA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 8 ASP A  13
ASP A 339
ILE A 104
ASP A  91
 MN  A 501 (-2.0A)
MN  A 501 (-2.2A)
None
TPO  A  92 ( 4.0A)
 1.02A 4xjeA-4n7tA:
2.7		 4xjeA-4n7tA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 12 ASP A 318
ILE A 324
ILE A  56
GLY A  57
LEU A  39
 None
 1.02A 4y8wC-4n7tA:
undetectable		 4y8wC-4n7tA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 12 LEU A 333
ILE A 325
PHE A 365
GLY A  78
LEU A 358
 None
 1.16A 4ze2A-4n7tA:
undetectable		 4ze2A-4n7tA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 ARG A 133
LYS A 130
GLU A 124
 None
 0.67A 5d0yA-4n7tA:
undetectable		 5d0yA-4n7tA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 12 LEU A 333
ILE A 325
PHE A 365
GLY A  78
LEU A 358
 None
 0.97A 5fsaA-4n7tA:
undetectable		 5fsaA-4n7tA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 12 VAL A 273
LEU A 294
GLY A 272
TYR A 310
LEU A  48
 AZI  A 506 (-4.8A)
None
None
None
None
 1.16A 5ienA-4n7tA:
undetectable		 5ienA-4n7tA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 11 VAL A  15
THR A 352
GLU A 354
TYR A 310
LEU A 314
 None
 1.04A 5jh7B-4n7tA:
undetectable		 5jh7B-4n7tA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 11 VAL A  15
THR A 352
GLU A 354
TYR A 310
LEU A 314
 None
 1.00A 5jh7D-4n7tA:
undetectable		 5jh7D-4n7tA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		5 / 12 ALA A 299
ILE A 383
PHE A 254
GLY A 101
HIS A 340
 None
None
None
None
MN  A 501 (-3.2A)
 1.03A 5jlcA-4n7tA:
1.0		 5jlcA-4n7tA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 8 LEU A   9
LEU A  83
ILE A 104
TRP A  97
 None
 1.00A 5ljbA-4n7tA:
undetectable		 5ljbA-4n7tA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 6 HIS A  96
ASN A 251
VAL A 247
LEU A 294
 TPO  A  92 ( 3.9A)
None
None
None
 1.37A 5xdhA-4n7tA:
undetectable
5xdhC-4n7tA:
undetectable		 5xdhA-4n7tA:
12.26
5xdhC-4n7tA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_1
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 THR A  38
GLU A 354
HIS A 340
 None
None
MN  A 501 (-3.2A)
 0.89A 5xioA-4n7tA:
undetectable		 5xioA-4n7tA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_B_HFGB1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 THR A  38
GLU A 354
HIS A 340
 None
None
MN  A 501 (-3.2A)
 0.87A 5xiqB-4n7tA:
undetectable		 5xiqB-4n7tA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		3 / 3 THR A  38
GLU A 354
HIS A 340
 None
None
MN  A 501 (-3.2A)
 0.88A 5xiqD-4n7tA:
undetectable		 5xiqD-4n7tA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 5 THR A  38
HIS A 340
ASP A 298
HIS A 351
 None
MN  A 501 (-3.2A)
MN  A 502 (-2.2A)
MN  A 502 (-3.2A)
 1.34A 6dchA-4n7tA:
undetectable		 6dchA-4n7tA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4n7t PHOSPHOPENTOMUTASE
(Streptococcus
mutans) 		4 / 7 ASP A  13
ASP A 339
LYS A 249
LYS A  93
 MN  A 501 (-2.0A)
MN  A 501 (-2.2A)
TPO  A  92 ( 3.6A)
TPO  A  92 ( 2.9A)
 1.19A 6g31A-4n7tA:
undetectable		 6g31A-4n7tA:
10.86