SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n8c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4n8c HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		4 / 8 GLN H  39
ASP H  46
SER H  44
TRP H 109
 None
 1.24A 2xz5A-4n8cH:
undetectable
2xz5C-4n8cH:
undetectable		 2xz5A-4n8cH:
25.10
2xz5C-4n8cH:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_D_PZID802_0
(GLUTAMATE RECEPTOR 2)		 4n8c HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		3 / 3 SER H  44
ASP H  46
ASN H  61
 None
 0.97A 3lslA-4n8cH:
undetectable
3lslD-4n8cH:
undetectable		 3lslA-4n8cH:
21.38
3lslD-4n8cH:
21.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 4n8c HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 108
 None
 0.36A 4m7kH-4n8cH:
23.0		 4m7kH-4n8cH:
63.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 4n8c HEAVY CHAIN OF
MONOCLONAL ANTIBODY
(Mus
musculus) 		3 / 3 SER H 209
ALA H 204
VAL H 203
 None
 0.52A 5xiwC-4n8cH:
undetectable		 5xiwC-4n8cH:
19.55