SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n8m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 4n8m NUCLEOPHOSMIN
(Mus
musculus) 		4 / 8 HIS A 110
LEU A  49
GLY A 107
ALA A  53
 None
 0.93A 2xfsA-4n8mA:
undetectable		 2xfsA-4n8mA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 4n8m NUCLEOPHOSMIN
(Mus
musculus) 		4 / 8 HIS A 110
LEU A  49
GLY A 107
ALA A  53
 None
 0.92A 2xh9A-4n8mA:
undetectable		 2xh9A-4n8mA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 4n8m NUCLEOPHOSMIN
(Mus
musculus) 		5 / 10 LEU A  57
HIS A  58
GLN A  84
THR A  78
LEU A  49
 None
 1.44A 3h9uA-4n8mA:
undetectable		 3h9uA-4n8mA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 4n8m NUCLEOPHOSMIN
(Mus
musculus) 		3 / 3 VAL A  87
ALA A  77
GLN A  84
 None
 0.71A 6gb9A-4n8mA:
undetectable		 6gb9A-4n8mA:
15.32