SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n91'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 11 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.96A 1akdA-4n91A:
undetectable		 1akdA-4n91A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 6 LEU A 254
TRP A 250
PHE A 262
VAL A 261
 None
 1.30A 1ibgH-4n91A:
undetectable		 1ibgH-4n91A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 7 GLN A 177
GLU A 214
PHE A 295
ALA A 151
 GCU  A 401 ( 3.4A)
None
None
GCU  A 401 (-3.6A)
 1.32A 1linA-4n91A:
undetectable		 1linA-4n91A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 11 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.95A 1phgA-4n91A:
undetectable		 1phgA-4n91A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 11 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.92A 2a1nA-4n91A:
undetectable		 2a1nA-4n91A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 10 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.95A 2cp4A-4n91A:
undetectable		 2cp4A-4n91A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_1
(UNCHARACTERIZED
PROTEIN PH0793)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		3 / 3 MET A 239
GLU A 217
ASP A 282
 None
 1.05A 3a25A-4n91A:
undetectable		 3a25A-4n91A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_A_DP0A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 12 TYR A 157
PHE A 198
VAL A 201
ALA A 151
SER A 219
 None
BDP  A 402 ( 3.6A)
None
GCU  A 401 (-3.6A)
GCU  A 401 ( 4.6A)
 1.47A 3apwA-4n91A:
undetectable		 3apwA-4n91A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 5 TYR A  64
ASP A 263
GLU A 136
GLU A 252
 None
 1.50A 3dh0B-4n91A:
undetectable		 3dh0B-4n91A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 10 ILE A  33
TRP A 250
ILE A  91
VAL A 261
LEU A 254
 None
 1.28A 3eqmA-4n91A:
undetectable		 3eqmA-4n91A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 11 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.79A 3lxiB-4n91A:
undetectable		 3lxiB-4n91A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 7 TYR A 325
VAL A 124
ILE A 134
ARG A 154
 None
None
None
GCU  A 401 ( 2.7A)
 1.08A 3mssB-4n91A:
undetectable		 3mssB-4n91A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 8 GLN A 238
PRO A 112
TYR A 113
GLN A 329
 None
 1.05A 3oyaA-4n91A:
undetectable		 3oyaA-4n91A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 12 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.90A 4c9lA-4n91A:
undetectable		 4c9lA-4n91A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 12 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.86A 4c9lB-4n91A:
undetectable		 4c9lB-4n91A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 10 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.87A 4c9nB-4n91A:
undetectable		 4c9nB-4n91A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 12 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.90A 4c9oA-4n91A:
undetectable		 4c9oA-4n91A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 12 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.90A 4c9oB-4n91A:
undetectable		 4c9oB-4n91A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 10 THR A 147
GLY A  48
VAL A  93
ASP A 242
VAL A 244
 None
None
None
GCU  A 401 ( 2.7A)
None
 0.83A 4c9pB-4n91A:
undetectable		 4c9pB-4n91A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 7 THR A 147
VAL A  93
ASP A 242
VAL A 244
 None
None
GCU  A 401 ( 2.7A)
None
 0.80A 4cp4A-4n91A:
undetectable		 4cp4A-4n91A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 6 PRO A 133
TYR A 331
PRO A 323
LEU A 321
 None
 1.21A 5tl8A-4n91A:
undetectable		 5tl8A-4n91A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		5 / 12 PHE A 115
ILE A 328
PHE A 109
ILE A 130
GLU A 119
 None
 1.11A 5vceA-4n91A:
0.0		 5vceA-4n91A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 5 ASN A 103
ASP A 104
ASN A 318
ASP A 319
 PG4  A 404 ( 4.9A)
None
None
None
 1.45A 5vooE-4n91A:
undetectable		 5vooE-4n91A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 5 PRO A  44
THR A  45
GLN A  39
MET A 218
 None
None
GCU  A 401 ( 3.7A)
None
 1.02A 6fgdA-4n91A:
undetectable		 6fgdA-4n91A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 4n91 TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT
(Anaerococcus
prevotii) 		4 / 8 ALA A 306
GLY A 190
LEU A 189
GLU A 167
 None
 0.82A 6mdqA-4n91A:
undetectable		 6mdqA-4n91A:
12.90