SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4n9g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4n9g ANTIBODY 17HD9,
HEAVY CHAIN
(Macaca
mulatta) 		4 / 8 ASN A  60
ILE A  48
GLY A 100
ARG A 100
 None
 0.96A 1meiA-4n9gA:
undetectable		 1meiA-4n9gA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4n9g ANTIBODY 17HD9,
HEAVY CHAIN
(Macaca
mulatta) 		4 / 7 ASN A  58
TYR A  56
ASN A  52
ARG A 100
 None
 0.99A 1wu8A-4n9gA:
undetectable
1wu8C-4n9gA:
undetectable		 1wu8A-4n9gA:
22.46
1wu8C-4n9gA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4n9g ANTIBODY 17HD9,
HEAVY CHAIN
(Macaca
mulatta) 		4 / 6 LEU A 189
GLY A 190
ALA A 125
PRO A 126
 None
 0.43A 3huoA-4n9gA:
undetectable		 3huoA-4n9gA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)		 4n9g ANTIBODY 17HD9,
HEAVY CHAIN
EPITOPE SCAFFOLD
RSV_1ISEA_FFL_001_C
(Macaca
mulatta;
synthetic
construct) 		4 / 5 TYR A  59
PRO C  75
THR C  77
THR A  35
 None
 1.50A 3q07A-4n9gA:
undetectable		 3q07A-4n9gA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)		 4n9g ANTIBODY 17HD9,
HEAVY CHAIN
EPITOPE SCAFFOLD
RSV_1ISEA_FFL_001_C
(Macaca
mulatta;
synthetic
construct) 		4 / 5 TYR A  59
PRO C  75
THR C  77
THR A  35
 None
 1.50A 3q07B-4n9gA:
undetectable		 3q07B-4n9gA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 4n9g ANTIBODY 17HD9,
HEAVY CHAIN
(Macaca
mulatta) 		4 / 5 TYR A  90
LEU A  77
LEU A  82
ARG A  66
 None
 1.26A 4em2A-4n9gA:
undetectable		 4em2A-4n9gA:
21.16