SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nav'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		4 / 4 GLY D  53
LEU D  51
GLY D  55
ARG D 160
 None
 1.21A 1j7kA-4navD:
undetectable		 1j7kA-4navD:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		4 / 7 VAL D 133
VAL D 166
LEU D 167
LEU D 114
 None
 0.85A 1pthA-4navD:
undetectable		 1pthA-4navD:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		4 / 7 VAL D 133
VAL D 166
LEU D 167
LEU D 114
 None
 0.84A 1pthB-4navD:
undetectable		 1pthB-4navD:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		4 / 5 PRO D 140
ILE D 142
ARG D 145
ASP D 119
 None
 1.37A 2rhmD-4navD:
undetectable		 2rhmD-4navD:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2O_C_AG2C1002_1
(BIOSYNTHETIC
ARGININE
DECARBOXYLASE)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		4 / 8 LYS D  95
LEU D 126
ASP D  26
ASP D 118
 None
 1.23A 3n2oC-4navD:
undetectable
3n2oD-4navD:
undetectable		 3n2oC-4navD:
14.49
3n2oD-4navD:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		5 / 12 LEU D 126
ASP D 122
VAL D 133
ALA D  98
LEU D  59
 None
 1.17A 4nc3A-4navD:
undetectable		 4nc3A-4navD:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		5 / 12 LEU D 126
ILE D  64
THR D  30
ALA D 159
LEU D  59
 None
 1.22A 5ienB-4navD:
undetectable		 5ienB-4navD:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6J_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		3 / 3 MET D 116
ASP D  52
ARG D 151
 None
 0.94A 5z6jA-4navD:
2.9		 5z6jA-4navD:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4nav HYPOTHETICAL PROTEIN
XCC279
(Xanthomonas
campestris) 		3 / 3 MET D 116
ASP D  52
ARG D 151
 None
 0.84A 5z6kA-4navD:
2.9		 5z6kA-4navD:
20.63