SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		4 / 8 ASN A 170
HIS A 294
SER A 169
VAL A 341
 None
 1.36A 1u1jA-4nbgA:
undetectable		 1u1jA-4nbgA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		4 / 7 ILE A 376
LEU A  49
ASN A   3
ASP A  20
 None
 0.98A 1yc2E-4nbgA:
undetectable		 1yc2E-4nbgA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		4 / 6 TRP A 285
GLY A 131
PHE A  34
SER A  35
 None
 0.74A 2a3cA-4nbgA:
undetectable		 2a3cA-4nbgA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		4 / 6 TRP A 285
GLY A 131
PHE A  34
SER A  35
 None
 0.76A 2a3cB-4nbgA:
undetectable		 2a3cB-4nbgA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		5 / 10 ALA A 369
GLN A 377
LEU A  49
SER A 370
ARG A 172
 None
 1.35A 2ceoB-4nbgA:
undetectable		 2ceoB-4nbgA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		4 / 8 LEU A 266
LEU A 368
ASP A 218
ASP A 219
 None
 1.07A 2j2pA-4nbgA:
undetectable
2j2pB-4nbgA:
undetectable		 2j2pA-4nbgA:
20.51
2j2pB-4nbgA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		5 / 9 GLY A 223
LEU A 266
LEU A 368
ASP A 218
ASP A 219
 None
 0.97A 2j2pB-4nbgA:
undetectable
2j2pC-4nbgA:
undetectable		 2j2pB-4nbgA:
20.51
2j2pC-4nbgA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		4 / 6 LEU A 173
GLU A 176
TRP A 350
PHE A 343
 None
 1.48A 3i9jB-4nbgA:
undetectable		 3i9jB-4nbgA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_ACTA303_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		3 / 3 TYR A 124
HIS A 381
ARG A  26
 None
 1.11A 4htfA-4nbgA:
undetectable		 4htfA-4nbgA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 4nbg TERMINAL OXYGENASE
COMPONENT OF
CARBAZOLE
(Janthinobacteriu
m
sp.
J3) 		3 / 3 ARG A 172
GLU A 353
TYR A  18
 None
 0.96A 4r29D-4nbgA:
undetectable		 4r29D-4nbgA:
19.43