SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DB1_A_VDXA428_1 (VITAMIN D NUCLEAR RECEPTOR)	4nbo	STEROID RECEPTOR RNA ACTIVATOR 1 (Homo sapiens)	5 / 12	LEU A 118 LEU A 115 VAL A 114 VAL A 198 LEU A 183	None	1.32A	1db1A-4nboA: undetectable	1db1A-4nboA: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_1 (RETINOIC ACID RECEPTOR, BETA)	4nbo	STEROID RECEPTOR RNA ACTIVATOR 1 (Homo sapiens)	5 / 12	CYH A 125 LEU A 201 ILE A 202 LEU A 164 LEU A 141	None	1.25A	1xdkB-4nboA: undetectable	1xdkB-4nboA: 16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M7R_A_VDXA425_1 (VITAMIN D3 RECEPTOR)	4nbo	STEROID RECEPTOR RNA ACTIVATOR 1 (Homo sapiens)	5 / 12	LEU A 118 LEU A 115 VAL A 114 VAL A 198 LEU A 183	None	1.26A	3m7rA-4nboA: undetectable	3m7rA-4nboA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L3G_F_ACTF401_0 (METHYLAMINE DEHYDROGENASE HEAVY CHAIN)	4nbo	STEROID RECEPTOR RNA ACTIVATOR 1 (Homo sapiens)	3 / 3	ARG A 126 LEU A 122 GLU A 123	None	0.54A	4l3gF-4nboA: undetectable	4l3gF-4nboA: 15.58

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DB1_A_VDXA428_1","VITAMIN D NUCLEAR RECEPTOR","4nbo","STEROID RECEPTOR RNA ACTIVATOR 1","Homo sapiens",5,"LEU A 118;LEU A 115;VAL A 114;VAL A 198;LEU A 183","None","1.32A","1db1A-4nboA:undetectable","1db1A-4nboA:20.31"],["1XDK_B_9CRB600_1","RETINOIC ACID RECEPTOR, BETA","4nbo","STEROID RECEPTOR RNA ACTIVATOR 1","Homo sapiens",5,"CYH A 125;LEU A 201;ILE A 202;LEU A 164;LEU A 141","None","1.25A","1xdkB-4nboA:undetectable","1xdkB-4nboA:16.27"],["3M7R_A_VDXA425_1","VITAMIN D3 RECEPTOR","4nbo","STEROID RECEPTOR RNA ACTIVATOR 1","Homo sapiens",5,"LEU A 118;LEU A 115;VAL A 114;VAL A 198;LEU A 183","None","1.26A","3m7rA-4nboA:undetectable","3m7rA-4nboA:17.65"],["4L3G_F_ACTF401_0","METHYLAMINE DEHYDROGENASE HEAVY CHAIN","4nbo","STEROID RECEPTOR RNA ACTIVATOR 1","Homo sapiens",3,"ARG A 126;LEU A 122;GLU A 123","None","0.54A","4l3gF-4nboA:undetectable","4l3gF-4nboA:15.58"]]