SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ndw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		3 / 3 ARG A  49
LEU A   9
THR A  15
 None
 0.89A 3oxcA-4ndwA:
undetectable		 3oxcA-4ndwA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		5 / 11 LEU A  48
LEU A  45
LEU A   9
ALA A  63
LEU A  64
 None
 1.17A 4wg0B-4ndwA:
undetectable
4wg0C-4ndwA:
undetectable
4wg0D-4ndwA:
undetectable		 4wg0B-4ndwA:
5.88
4wg0C-4ndwA:
5.88
4wg0D-4ndwA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		5 / 11 LEU A  48
LEU A  45
LEU A   9
ALA A  63
LEU A  64
 None
 1.20A 4wg0D-4ndwA:
undetectable
4wg0E-4ndwA:
undetectable
4wg0F-4ndwA:
undetectable		 4wg0D-4ndwA:
5.88
4wg0E-4ndwA:
5.88
4wg0F-4ndwA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		5 / 11 LEU A  48
LEU A  45
LEU A   9
ALA A  63
LEU A  64
 None
 1.19A 4wg0F-4ndwA:
undetectable
4wg0G-4ndwA:
undetectable
4wg0H-4ndwA:
undetectable		 4wg0F-4ndwA:
5.88
4wg0G-4ndwA:
5.88
4wg0H-4ndwA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		5 / 11 LEU A  48
LEU A  45
LEU A   9
ALA A  63
LEU A  64
 None
 1.21A 4wg0H-4ndwA:
undetectable
4wg0I-4ndwA:
undetectable
4wg0J-4ndwA:
undetectable		 4wg0H-4ndwA:
5.88
4wg0I-4ndwA:
5.88
4wg0J-4ndwA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		5 / 11 ALA A  63
LEU A  64
LEU A   9
LEU A  48
LEU A  45
 None
 1.19A 4wg0G-4ndwA:
undetectable
4wg0H-4ndwA:
undetectable
4wg0I-4ndwA:
undetectable		 4wg0G-4ndwA:
5.88
4wg0H-4ndwA:
5.88
4wg0I-4ndwA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		5 / 11 ALA A  63
LEU A  64
LEU A   9
LEU A  48
LEU A  45
 None
 1.20A 4wg0I-4ndwA:
undetectable
4wg0J-4ndwA:
undetectable
4wg0K-4ndwA:
undetectable		 4wg0I-4ndwA:
5.88
4wg0J-4ndwA:
5.88
4wg0K-4ndwA:
5.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		4 / 7 LEU A   9
MET A  61
ALA A  65
ILE A  70
 None
 0.75A 4y03A-4ndwA:
undetectable		 4y03A-4ndwA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_E_SAME501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4ndw NUCLEOID-ASSOCIATED
PROTEIN ESPR
(Mycobacterium
tuberculosis) 		5 / 9 LEU A  48
PRO A  56
GLY A  51
LEU A   9
ARG A  11
 None
 1.40A 5o96E-4ndwA:
undetectable
5o96F-4ndwA:
undetectable		 5o96E-4ndwA:
19.76
5o96F-4ndwA:
19.76