SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nec'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICT_D_T44D129_2 (TRANSTHYRETIN)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	4 / 7	LEU A 218 THR A 107 LEU A 142 SER A 111	None None None SAH A 401 (-3.3A)	0.78A	1ictD-4necA: undetectable	1ictD-4necA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_B_ACTB1873_0 (FPRA)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	3 / 3	ASP A 181 ASP A 185 LYS A 177	None	1.16A	1lqtB-4necA: undetectable	1lqtB-4necA: 22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TYR_B_9CRB130_1 (TRANSTHYRETIN)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	4 / 7	LEU A 218 THR A 107 LEU A 142 SER A 111	None None None SAH A 401 (-3.3A)	0.86A	1tyrB-4necA: undetectable	1tyrB-4necA: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZQ9_B_SAMB4001_0 (PROBABLE DIMETHYLADENOSINE TRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 LEU A 69 ASP A 94 LEU A 113	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 (-3.7A) SAH A 401 ( 3.6A) SAH A 401 (-4.1A)	0.88A	1zq9B-4necA: 10.9	1zq9B-4necA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_A_SAMA298_0 (PUTATIVE MODIFICATION METHYLASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	ALA A 95 SER A 111 GLY A 49 THR A 50 LEU A 69	SAH A 401 (-3.2A) SAH A 401 (-3.3A) SAH A 401 (-3.6A) None SAH A 401 (-3.7A)	0.65A	2zifA-4necA: 5.1	2zifA-4necA: 23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZIF_B_SAMB298_0 (PUTATIVE MODIFICATION METHYLASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	ALA A 95 SER A 111 GLY A 49 THR A 50 LEU A 69	SAH A 401 (-3.2A) SAH A 401 (-3.3A) SAH A 401 (-3.6A) None SAH A 401 (-3.7A)	0.68A	2zifB-4necA: 5.0	2zifB-4necA: 23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6H_A_MXDA551_1 (PROSTACYCLIN SYNTHASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	4 / 6	TYR A 125 ALA A 126 LEU A 129 ALA A 139	None	0.72A	3b6hA-4necA: undetectable	3b6hA-4necA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DLC_A_SAMA220_0 (PUTATIVE S-ADENOSYL-L-METHION INE-DEPENDENT METHYLTRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	PHE A 5 GLY A 47 GLY A 49 SER A 70 ASP A 94	SAH A 401 ( 3.5A) SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 ( 4.8A) SAH A 401 ( 3.6A)	0.41A	3dlcA-4necA: 16.8	3dlcA-4necA: 20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G2O_B_SAMB600_0 (PCZA361.24)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 49 LEU A 69 ASP A 94 SER A 111 GLY A 112	SAH A 401 (-3.6A) SAH A 401 (-3.7A) SAH A 401 ( 3.6A) SAH A 401 (-3.3A) SAH A 401 (-4.6A)	0.93A	3g2oB-4necA: 16.4	3g2oB-4necA: 29.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IHT_A_SAMA200_0 (S-ADENOSYL-L-METHION INE METHYL TRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	6 / 12	GLY A 47 GLY A 49 GLY A 51 ASP A 94 LEU A 113 PHE A 117	SAH A 401 (-3.9A) SAH A 401 (-3.6A) None SAH A 401 ( 3.6A) SAH A 401 (-4.1A) None	0.86A	3ihtA-4necA: 8.3	3ihtA-4necA: 27.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_C_SAMC300_1 (SAM-DEPENDENT METHYLTRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	3 / 3	GLY A 49 ASP A 68 ASP A 94	SAH A 401 (-3.6A) SAH A 401 (-2.8A) SAH A 401 ( 3.6A)	0.35A	3ou7C-4necA: 15.7	3ou7C-4necA: 29.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CP4_A_CAMA416_0 (CYTOCHROME P450-CAM)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	4 / 7	THR A 107 VAL A 64 ASP A 45 VAL A 43	None None SAH A 401 ( 4.7A) None	1.00A	4cp4A-4necA: undetectable	4cp4A-4necA: 21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA501_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	4 / 5	LEU A 113 TYR A 125 LEU A 96 ARG A 121	SAH A 401 (-4.1A) None SAH A 401 ( 4.5A) None	1.18A	4em2A-4necA: undetectable	4em2A-4necA: 19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_B_CQAB301_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	4 / 8	GLY A 51 GLY A 47 TYR A 125 LEU A 113	None SAH A 401 (-3.9A) None SAH A 401 (-4.1A)	0.92A	4fgzB-4necA: 16.6	4fgzB-4necA: 19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_A_SAMA301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 LEU A 69 SER A 70 ALA A 95	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 (-3.7A) SAH A 401 ( 4.8A) SAH A 401 (-3.2A)	0.43A	4htfA-4necA: 16.1	4htfA-4necA: 26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HTF_B_SAMB301_0 (S-ADENOSYLMETHIONINE -DEPENDENT METHYLTRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 LEU A 69 SER A 70 ALA A 95	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 (-3.7A) SAH A 401 ( 4.8A) SAH A 401 (-3.2A)	0.37A	4htfB-4necA: 16.0	4htfB-4necA: 26.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	6 / 12	GLY A 47 GLY A 49 LEU A 69 SER A 70 ASP A 94 ALA A 95	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 (-3.7A) SAH A 401 ( 4.8A) SAH A 401 ( 3.6A) SAH A 401 (-3.2A)	0.61A	4krhA-4necA: 16.7	4krhA-4necA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	6 / 12	TYR A 9 GLY A 47 LEU A 69 SER A 70 ASP A 94 ALA A 95	SAH A 401 (-4.4A) SAH A 401 (-3.9A) SAH A 401 (-3.7A) SAH A 401 ( 4.8A) SAH A 401 ( 3.6A) SAH A 401 (-3.2A)	1.20A	4krhA-4necA: 16.7	4krhA-4necA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 LEU A 69 SER A 70 ALA A 95	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 (-3.7A) SAH A 401 ( 4.8A) SAH A 401 (-3.2A)	0.43A	4krhB-4necA: 16.9	4krhB-4necA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_B_SAMB900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	TYR A 9 GLY A 47 LEU A 69 SER A 70 ALA A 95	SAH A 401 (-4.4A) SAH A 401 (-3.9A) SAH A 401 (-3.7A) SAH A 401 ( 4.8A) SAH A 401 (-3.2A)	0.90A	4krhB-4necA: 16.9	4krhB-4necA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NQA_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 11	ARG A 184 LEU A 183 ALA A 180 VAL A 108 LEU A 33	None	1.04A	4nqaA-4necA: undetectable	4nqaA-4necA: 23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_D_SAMD301_0 (PUTATIVE METHYLTRANSFERASE BUD23)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 SER A 70 SER A 111 ARG A 121	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 ( 4.8A) SAH A 401 (-3.3A) None	1.16A	4qtuD-4necA: 16.3	4qtuD-4necA: 25.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 GLY A 51 LEU A 69 ALA A 95	SAH A 401 (-3.9A) SAH A 401 (-3.6A) None SAH A 401 (-3.7A) SAH A 401 (-3.2A)	0.60A	4uciA-4necA: 7.1	4uciA-4necA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCI_B_SAMB2409_0 (RNA-DIRECTED RNA POLYMERASE L)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 GLY A 51 LEU A 69 ALA A 95	SAH A 401 (-3.9A) SAH A 401 (-3.6A) None SAH A 401 (-3.7A) SAH A 401 (-3.2A)	0.58A	4uciB-4necA: 7.0	4uciB-4necA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_0 (RNA-DIRECTED RNA POLYMERASE L)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 GLY A 51 LEU A 69 ALA A 95	SAH A 401 (-3.9A) SAH A 401 (-3.6A) None SAH A 401 (-3.7A) SAH A 401 (-3.2A)	0.61A	4uckA-4necA: 6.9	4uckA-4necA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E72_A_SAMA400_1 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	4 / 4	ASP A 45 GLY A 49 ASP A 68 ASP A 94	SAH A 401 ( 4.7A) SAH A 401 (-3.6A) SAH A 401 (-2.8A) SAH A 401 ( 3.6A)	0.71A	5e72A-4necA: 14.6	5e72A-4necA: 23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TRQ_B_ACTB307_0 (WELO5)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	3 / 3	GLU A 151 HIS A 215 VAL A 214	None	0.89A	5trqB-4necA: undetectable	5trqB-4necA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B3A_A_SAMA701_0 (APRA METHYLTRANSFERASE 1)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 ALA A 73 ASP A 94 LEU A 113	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 ( 4.8A) SAH A 401 ( 3.6A) SAH A 401 (-4.1A)	0.74A	6b3aA-4necA: 2.6	6b3aA-4necA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B3B_A_SAMA701_0 (APRA METHYLTRANSFERASE 1)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 GLY A 49 ALA A 73 ASP A 94 LEU A 113	SAH A 401 (-3.9A) SAH A 401 (-3.6A) SAH A 401 ( 4.8A) SAH A 401 ( 3.6A) SAH A 401 (-4.1A)	0.74A	6b3bA-4necA: 3.2	6b3bA-4necA: 18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_A_ADNA401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 ASP A 68 ASP A 94 ALA A 95 LEU A 113	SAH A 401 (-3.9A) SAH A 401 (-2.8A) SAH A 401 ( 3.6A) SAH A 401 (-3.2A) SAH A 401 (-4.1A)	0.93A	6bq4A-4necA: 9.8	6bq4A-4necA: 15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BQ4_B_ADNB401_1 (THERMOSPERMINE SYNTHASE ACAULIS PROTEIN)	4nec	PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE (Streptomyces lasaliensis)	5 / 12	GLY A 47 ASP A 68 ASP A 94 ALA A 95 LEU A 113	SAH A 401 (-3.9A) SAH A 401 (-2.8A) SAH A 401 ( 3.6A) SAH A 401 (-3.2A) SAH A 401 (-4.1A)	0.96A	6bq4B-4necA: 9.1	6bq4B-4necA: 15.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ICT_D_T44D129_2","TRANSTHYRETIN","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",4,"LEU A 218;THR A 107;LEU A 142;SER A 111","None;None;None;SAH A 401 (-3.3A)","0.78A","1ictD-4necA:undetectable","1ictD-4necA:22.14"],["1LQT_B_ACTB1873_0","FPRA","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",3,"ASP A 181;ASP A 185;LYS A 177","None","1.16A","1lqtB-4necA:undetectable","1lqtB-4necA:22.15"],["1TYR_B_9CRB130_1","TRANSTHYRETIN","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",4,"LEU A 218;THR A 107;LEU A 142;SER A 111","None;None;None;SAH A 401 (-3.3A)","0.86A","1tyrB-4necA:undetectable","1tyrB-4necA:22.14"],["1ZQ9_B_SAMB4001_0","PROBABLE DIMETHYLADENOSINE TRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;LEU A  69;ASP A  94;LEU A 113","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 (-3.7A);SAH A 401 ( 3.6A);SAH A 401 (-4.1A)","0.88A","1zq9B-4necA:10.9","1zq9B-4necA:20.60"],["2ZIF_A_SAMA298_0","PUTATIVE MODIFICATION METHYLASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"ALA A  95;SER A 111;GLY A  49;THR A  50;LEU A  69","SAH A 401 (-3.2A);SAH A 401 (-3.3A);SAH A 401 (-3.6A);None;SAH A 401 (-3.7A)","0.65A","2zifA-4necA:5.1","2zifA-4necA:23.95"],["2ZIF_B_SAMB298_0","PUTATIVE MODIFICATION METHYLASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"ALA A  95;SER A 111;GLY A  49;THR A  50;LEU A  69","SAH A 401 (-3.2A);SAH A 401 (-3.3A);SAH A 401 (-3.6A);None;SAH A 401 (-3.7A)","0.68A","2zifB-4necA:5.0","2zifB-4necA:23.95"],["3B6H_A_MXDA551_1","PROSTACYCLIN SYNTHASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",4,"TYR A 125;ALA A 126;LEU A 129;ALA A 139","None","0.72A","3b6hA-4necA:undetectable","3b6hA-4necA:20.74"],["3DLC_A_SAMA220_0","PUTATIVE S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"PHE A   5;GLY A  47;GLY A  49;SER A  70;ASP A  94","SAH A 401 ( 3.5A);SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 ( 4.8A);SAH A 401 ( 3.6A)","0.41A","3dlcA-4necA:16.8","3dlcA-4necA:20.30"],["3G2O_B_SAMB600_0","PCZA361.24","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  49;LEU A  69;ASP A  94;SER A 111;GLY A 112","SAH A 401 (-3.6A);SAH A 401 (-3.7A);SAH A 401 ( 3.6A);SAH A 401 (-3.3A);SAH A 401 (-4.6A)","0.93A","3g2oB-4necA:16.4","3g2oB-4necA:29.60"],["3IHT_A_SAMA200_0","S-ADENOSYL-L-METHIONINE METHYL TRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",6,"GLY A  47;GLY A  49;GLY A  51;ASP A  94;LEU A 113;PHE A 117","SAH A 401 (-3.9A);SAH A 401 (-3.6A);None;SAH A 401 ( 3.6A);SAH A 401 (-4.1A);None","0.86A","3ihtA-4necA:8.3","3ihtA-4necA:27.34"],["3OU7_C_SAMC300_1","SAM-DEPENDENT METHYLTRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",3,"GLY A  49;ASP A  68;ASP A  94","SAH A 401 (-3.6A);SAH A 401 (-2.8A);SAH A 401 ( 3.6A)","0.35A","3ou7C-4necA:15.7","3ou7C-4necA:29.82"],["4CP4_A_CAMA416_0","CYTOCHROME P450-CAM","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",4,"THR A 107;VAL A  64;ASP A  45;VAL A  43","None;None;SAH A 401 ( 4.7A);None","1.00A","4cp4A-4necA:undetectable","4cp4A-4necA:21.68"],["4EM2_A_SALA501_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",4,"LEU A 113;TYR A 125;LEU A  96;ARG A 121","SAH A 401 (-4.1A);None;SAH A 401 ( 4.5A);None","1.18A","4em2A-4necA:undetectable","4em2A-4necA:19.15"],["4FGZ_B_CQAB301_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",4,"GLY A  51;GLY A  47;TYR A 125;LEU A 113","None;SAH A 401 (-3.9A);None;SAH A 401 (-4.1A)","0.92A","4fgzB-4necA:16.6","4fgzB-4necA:19.65"],["4HTF_A_SAMA301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;LEU A  69;SER A  70;ALA A  95","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 (-3.7A);SAH A 401 ( 4.8A);SAH A 401 (-3.2A)","0.43A","4htfA-4necA:16.1","4htfA-4necA:26.42"],["4HTF_B_SAMB301_0","S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;LEU A  69;SER A  70;ALA A  95","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 (-3.7A);SAH A 401 ( 4.8A);SAH A 401 (-3.2A)","0.37A","4htfB-4necA:16.0","4htfB-4necA:26.42"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",6,"GLY A  47;GLY A  49;LEU A  69;SER A  70;ASP A  94;ALA A  95","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 (-3.7A);SAH A 401 ( 4.8A);SAH A 401 ( 3.6A);SAH A 401 (-3.2A)","0.61A","4krhA-4necA:16.7","4krhA-4necA:21.38"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",6,"TYR A   9;GLY A  47;LEU A  69;SER A  70;ASP A  94;ALA A  95","SAH A 401 (-4.4A);SAH A 401 (-3.9A);SAH A 401 (-3.7A);SAH A 401 ( 4.8A);SAH A 401 ( 3.6A);SAH A 401 (-3.2A)","1.20A","4krhA-4necA:16.7","4krhA-4necA:21.38"],["4KRH_B_SAMB900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;LEU A  69;SER A  70;ALA A  95","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 (-3.7A);SAH A 401 ( 4.8A);SAH A 401 (-3.2A)","0.43A","4krhB-4necA:16.9","4krhB-4necA:21.38"],["4KRH_B_SAMB900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"TYR A   9;GLY A  47;LEU A  69;SER A  70;ALA A  95","SAH A 401 (-4.4A);SAH A 401 (-3.9A);SAH A 401 (-3.7A);SAH A 401 ( 4.8A);SAH A 401 (-3.2A)","0.90A","4krhB-4necA:16.9","4krhB-4necA:21.38"],["4NQA_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"ARG A 184;LEU A 183;ALA A 180;VAL A 108;LEU A  33","None","1.04A","4nqaA-4necA:undetectable","4nqaA-4necA:23.24"],["4QTU_D_SAMD301_0","PUTATIVE METHYLTRANSFERASE BUD23","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;SER A  70;SER A 111;ARG A 121","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 ( 4.8A);SAH A 401 (-3.3A);None","1.16A","4qtuD-4necA:16.3","4qtuD-4necA:25.89"],["4UCI_A_SAMA2409_0","RNA-DIRECTED RNA POLYMERASE L","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;GLY A  51;LEU A  69;ALA A  95","SAH A 401 (-3.9A);SAH A 401 (-3.6A);None;SAH A 401 (-3.7A);SAH A 401 (-3.2A)","0.60A","4uciA-4necA:7.1","4uciA-4necA:20.28"],["4UCI_B_SAMB2409_0","RNA-DIRECTED RNA POLYMERASE L","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;GLY A  51;LEU A  69;ALA A  95","SAH A 401 (-3.9A);SAH A 401 (-3.6A);None;SAH A 401 (-3.7A);SAH A 401 (-3.2A)","0.58A","4uciB-4necA:7.0","4uciB-4necA:20.28"],["4UCK_A_SAMA2409_0","RNA-DIRECTED RNA POLYMERASE L","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;GLY A  51;LEU A  69;ALA A  95","SAH A 401 (-3.9A);SAH A 401 (-3.6A);None;SAH A 401 (-3.7A);SAH A 401 (-3.2A)","0.61A","4uckA-4necA:6.9","4uckA-4necA:20.28"],["5E72_A_SAMA400_1","N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",4,"ASP A  45;GLY A  49;ASP A  68;ASP A  94","SAH A 401 ( 4.7A);SAH A 401 (-3.6A);SAH A 401 (-2.8A);SAH A 401 ( 3.6A)","0.71A","5e72A-4necA:14.6","5e72A-4necA:23.51"],["5TRQ_B_ACTB307_0","WELO5","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",3,"GLU A 151;HIS A 215;VAL A 214","None","0.89A","5trqB-4necA:undetectable","5trqB-4necA:20.33"],["6B3A_A_SAMA701_0","APRA METHYLTRANSFERASE 1","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;ALA A  73;ASP A  94;LEU A 113","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 ( 4.8A);SAH A 401 ( 3.6A);SAH A 401 (-4.1A)","0.74A","6b3aA-4necA:2.6","6b3aA-4necA:18.20"],["6B3B_A_SAMA701_0","APRA METHYLTRANSFERASE 1","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;GLY A  49;ALA A  73;ASP A  94;LEU A 113","SAH A 401 (-3.9A);SAH A 401 (-3.6A);SAH A 401 ( 4.8A);SAH A 401 ( 3.6A);SAH A 401 (-4.1A)","0.74A","6b3bA-4necA:3.2","6b3bA-4necA:18.20"],["6BQ4_A_ADNA401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;ASP A  68;ASP A  94;ALA A  95;LEU A 113","SAH A 401 (-3.9A);SAH A 401 (-2.8A);SAH A 401 ( 3.6A);SAH A 401 (-3.2A);SAH A 401 (-4.1A)","0.93A","6bq4A-4necA:9.8","6bq4A-4necA:15.75"],["6BQ4_B_ADNB401_1","THERMOSPERMINE SYNTHASE ACAULIS PROTEIN","4nec","PUTATIVE SAM-DEPENDENT METHYLTRANSFERASE","Streptomyces lasaliensis",5,"GLY A  47;ASP A  68;ASP A  94;ALA A  95;LEU A 113","SAH A 401 (-3.9A);SAH A 401 (-2.8A);SAH A 401 ( 3.6A);SAH A 401 (-3.2A);SAH A 401 (-4.1A)","0.96A","6bq4B-4necA:9.1","6bq4B-4necA:15.75"]]