SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nf0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 122
LEU A 131
PHE A 113
SER A  95
 None
 1.29A 1wrkB-4nf0A:
undetectable		 1wrkB-4nf0A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 HIS A  35
PHE A  33
GLY A  46
LYS A  45
 None
 1.12A 2i30A-4nf0A:
undetectable		 2i30A-4nf0A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 151
SER A  93
GLN A 173
 None
LMR  A 401 (-4.0A)
LMR  A 401 (-3.6A)
 1.38A 3si7A-4nf0A:
undetectable		 3si7A-4nf0A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 286
GLY A 288
LEU A 284
ASP A 222
ILE A 228
 None
 1.21A 3wdmA-4nf0A:
undetectable		 3wdmA-4nf0A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 286
GLY A 288
LEU A 284
ASP A 222
ILE A 228
 None
 1.19A 3wdmC-4nf0A:
undetectable		 3wdmC-4nf0A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 VAL A 262
LEU A 240
LEU A 143
ILE A  31
 None
 0.93A 4a9jC-4nf0A:
undetectable		 4a9jC-4nf0A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 171
GLY A 208
GLN A 181
MET A 307
 LMR  A 401 (-2.9A)
None
None
None
 0.86A 4g0vB-4nf0A:
undetectable		 4g0vB-4nf0A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 GLU A 210
THR A 209
GLN A 173
ASN A 148
 None
None
LMR  A 401 (-3.6A)
None
 1.11A 4pfjB-4nf0A:
undetectable		 4pfjB-4nf0A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 149
ALA A 273
ARG A 281
GLU A 230
LEU A 119
 None
 0.97A 4uw0A-4nf0A:
undetectable		 4uw0A-4nf0A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 182
ILE A 172
GLY A 208
LEU A 216
 None
 0.93A 4zdzA-4nf0A:
undetectable		 4zdzA-4nf0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE3_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 182
ILE A 172
GLY A 208
LEU A 216
 None
 0.92A 4ze3A-4nf0A:
undetectable		 4ze3A-4nf0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 182
ILE A 172
GLY A 208
LEU A 216
 None
 0.90A 5esjA-4nf0A:
undetectable		 5esjA-4nf0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 PHE A 182
ILE A 172
GLY A 208
LEU A 216
 None
 0.95A 5esmA-4nf0A:
undetectable		 5esmA-4nf0A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.64A 5qgjA-4nf0A:
undetectable		 5qgjA-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.58A 5qgnA-4nf0A:
undetectable		 5qgnA-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.57A 5qgyA-4nf0A:
undetectable		 5qgyA-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.58A 5qgzA-4nf0A:
undetectable		 5qgzA-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.60A 5qh0A-4nf0A:
undetectable		 5qh0A-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.57A 5qh2A-4nf0A:
undetectable		 5qh2A-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.58A 5qh3A-4nf0A:
undetectable		 5qh3A-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.55A 5qh5A-4nf0A:
undetectable		 5qh5A-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.59A 5qh6A-4nf0A:
undetectable		 5qh6A-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.58A 5qh7A-4nf0A:
undetectable		 5qh7A-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.64A 5qhaA-4nf0A:
undetectable		 5qhaA-4nf0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4nf0 PROBABLE
C4-DICARBOXYLATE-BIN
DING PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 VAL A  62
VAL A  29
GLN A  88
 None
 0.61A 5qhhA-4nf0A:
undetectable		 5qhhA-4nf0A:
20.83