SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nf7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		4 / 7 ASN A 138
ASN A  51
HIS A 273
VAL A 318
 None
 1.23A 1wu8A-4nf7A:
undetectable
1wu8C-4nf7A:
undetectable		 1wu8A-4nf7A:
21.78
1wu8C-4nf7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA2_A_SCKA901_1
(ACETYLCHOLINESTERASE)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		4 / 8 ASP A 384
TRP A 382
TYR A 360
HIS A 372
 None
 1.38A 2ha2A-4nf7A:
undetectable		 2ha2A-4nf7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		5 / 12 ASN A 188
GLU A 189
HIS A 273
GLU A 321
TRP A 355
 None
 0.60A 2v3dA-4nf7A:
17.7		 2v3dA-4nf7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		4 / 7 VAL A 121
TYR A 127
CYH A 128
ILE A  52
 None
 1.27A 2xz5B-4nf7A:
undetectable
2xz5E-4nf7A:
undetectable		 2xz5B-4nf7A:
22.59
2xz5E-4nf7A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		4 / 7 LEU A 268
VAL A 240
THR A 186
ASP A 226
 None
 0.90A 2zaxA-4nf7A:
undetectable		 2zaxA-4nf7A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		3 / 3 GLY A  53
ASP A  57
SER A  58
 None
 0.65A 3brfA-4nf7A:
undetectable		 3brfA-4nf7A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		3 / 3 ARG A 333
ARG A 327
ILE A 387
 None
 0.79A 4b7qC-4nf7A:
undetectable		 4b7qC-4nf7A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_2
(DIPEPTIDYL PEPTIDASE
4)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		3 / 3 PHE A  65
TYR A  74
TYR A  67
 None
 1.10A 4ffwA-4nf7A:
undetectable		 4ffwA-4nf7A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		4 / 6 ILE A 228
ILE A 167
SER A 139
LEU A 137
 None
 0.97A 4m51A-4nf7A:
7.0		 4m51A-4nf7A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		4 / 4 GLY A 103
LEU A 137
PHE A 184
ILE A 171
 None
 0.94A 4xv2A-4nf7A:
undetectable		 4xv2A-4nf7A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		5 / 12 TYR A 340
GLY A 320
ILE A 136
VAL A 318
VAL A 183
 None
 1.15A 5dpdA-4nf7A:
undetectable		 5dpdA-4nf7A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_A_BEZA201_0
(HYDROXYNITRILE LYASE)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		5 / 9 VAL A 125
VAL A 121
ILE A 171
PHE A 184
LEU A 182
 None
 1.32A 5e4dA-4nf7A:
undetectable		 5e4dA-4nf7A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		3 / 3 THR A  35
THR A 237
ARG A 267
 None
 1.00A 5wm2A-4nf7A:
2.0		 5wm2A-4nf7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		4 / 7 ASN A 378
ASP A 356
GLY A  53
ASN A  77
 None
 1.11A 5x7pA-4nf7A:
undetectable		 5x7pA-4nf7A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 4nf7 ENDO-1,4-BETA-GLUCAN
ASE CEL5C
(Butyrivibrio
proteoclasticus) 		3 / 3 GLU A 189
TRP A 199
HIS A 141
 None
 0.98A 5xipA-4nf7A:
undetectable		 5xipA-4nf7A:
21.50