SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nfd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA
(Homo
sapiens) 		4 / 7 LEU A  80
PHE A  94
PHE A  51
ILE A  82
 None
 0.98A 2opxA-4nfdA:
undetectable		 2opxA-4nfdA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA
(Homo
sapiens) 		3 / 3 ASP A  89
LEU A 117
GLN A   7
 None
 0.83A 3g4lA-4nfdA:
undetectable		 3g4lA-4nfdA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA
(Homo
sapiens) 		4 / 8 SER A  40
ILE A  39
PHE A  25
GLU A  98
 None
 1.27A 4cx7A-4nfdA:
undetectable
4cx7B-4nfdA:
undetectable		 4cx7A-4nfdA:
15.25
4cx7B-4nfdA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA
(Homo
sapiens) 		4 / 7 PHE A  25
GLY A  74
ILE A  39
PHE A  23
 None
 0.82A 4ejjA-4nfdA:
undetectable		 4ejjA-4nfdA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA
(Homo
sapiens) 		4 / 7 ARG A  86
ASP A  89
ILE A  82
TYR A  93
 None
 1.24A 5a06B-4nfdA:
undetectable		 5a06B-4nfdA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA
(Homo
sapiens) 		4 / 5 ARG A  96
TYR A   3
GLN A 110
ILE A 112
 SIA  A 201 (-3.0A)
SIA  A 201 (-3.4A)
None
None
 1.25A 6f6sA-4nfdA:
undetectable
6f6sB-4nfdA:
undetectable		 6f6sA-4nfdA:
20.83
6f6sB-4nfdA:
20.00