SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 SER D 351
SER D 350
VAL D 378
PHE D 389
 None
 1.38A 1oipA-4ngeD:
undetectable		 1oipA-4ngeD:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 THR D 354
PHE D 361
PHE D 420
LEU D 334
 None
 1.08A 1qcaA-4ngeD:
undetectable		 1qcaA-4ngeD:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RB2_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ILE D 758
ALA D 753
PHE D 699
LEU D 765
ILE D 761
 None
MLY  D 704 ( 3.9A)
None
MLY  D 764 ( 4.1A)
None
 1.03A 1rb2B-4ngeD:
undetectable		 1rb2B-4ngeD:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 VAL D 201
GLY D 200
VAL D 202
TRP D 182
 None
 1.04A 1tkqB-4ngeD:
undetectable		 1tkqB-4ngeD:
3.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWJ_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 ILE D 885
ASP D 951
PHE D 947
 MLY  D 884 ( 4.0A)
None
MLY  D 946 ( 4.7A)
 0.59A 1uwjB-4ngeD:
1.8		 1uwjB-4ngeD:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 ALA D 137
HIS D 108
HIS D 104
GLU D 205
TYR D 906
 None
 0.57A 2c6nA-4ngeD:
undetectable		 2c6nA-4ngeD:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D06_A_ESTA304_1
(SULFOTRANSFERASE 1A1)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 PHE D  92
PRO D 170
HIS D 254
PHE D 169
ALA D 284
 None
None
None
MLY  D 287 ( 4.5A)
None
 1.36A 2d06A-4ngeD:
undetectable		 2d06A-4ngeD:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D06_B_ESTB305_1
(SULFOTRANSFERASE 1A1)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 10 PHE D  92
PRO D 170
HIS D 254
PHE D 169
ALA D 284
 None
None
None
MLY  D 287 ( 4.5A)
None
 1.36A 2d06B-4ngeD:
undetectable		 2d06B-4ngeD:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 VAL D 489
LEU D 352
PHE D 484
THR D 345
 MLY  D 488 ( 3.3A)
None
MLY  D 488 ( 4.8A)
None
 1.07A 2f78A-4ngeD:
undetectable		 2f78A-4ngeD:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 PHE D 740
SER D 741
ALA D 733
LEU D 736
 None
 1.05A 2o01A-4ngeD:
undetectable		 2o01A-4ngeD:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 ALA D  64
THR D  63
ALA D  80
TYR D  40
 None
 0.80A 2ql8A-4ngeD:
4.1
2ql8B-4ngeD:
4.1		 2ql8A-4ngeD:
9.49
2ql8B-4ngeD:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 ILE D 687
PRO D 766
ILE D 768
PHE D 668
VAL D 585
 None
MLY  D 764 ( 4.5A)
MLY  D 769 ( 3.8A)
None
None
 1.23A 2ygpA-4ngeD:
undetectable		 2ygpA-4ngeD:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 THR D 872
SER D 882
LYS D 885
 None
None
MLY  D 884 ( 3.1A)
 1.17A 3aocC-4ngeD:
5.2		 3aocC-4ngeD:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_1
(MODIFICATION
METHYLASE HHAI)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		3 / 3 GLU D 709
SER D 620
VAL D 621
 None
 0.73A 3eeoA-4ngeD:
undetectable		 3eeoA-4ngeD:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 ILE D 803
PHE D 799
ASP D 798
GLU D 797
 None
None
MLY  D 794 ( 3.0A)
None
 1.10A 3kp6A-4ngeD:
1.6
3kp6B-4ngeD:
1.3		 3kp6A-4ngeD:
9.61
3kp6B-4ngeD:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		6 / 9 ALA D 955
ASP D 951
ILE D 952
ILE D 565
VAL D 996
ILE D 885
 None
None
None
None
None
MLY  D 884 ( 4.0A)
 1.31A 3nu4A-4ngeD:
undetectable		 3nu4A-4ngeD:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 TYR D 362
THR D 354
PHE D 361
LEU D 393
 None
 1.37A 3qelC-4ngeD:
undetectable		 3qelC-4ngeD:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP6_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 THR D 144
VAL D  90
HIS D 457
VAL D 297
TYR D 231
 None
 1.34A 3sp6A-4ngeD:
undetectable		 3sp6A-4ngeD:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 LEU D 160
PHE D 168
PHE D 288
LEU D 145
THR D 167
 None
None
MLY  D 287 ( 4.0A)
None
None
 1.43A 4iaqA-4ngeD:
2.6		 4iaqA-4ngeD:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 GLN D 949
ASP D 951
ILE D 952
ILE D 885
 None
None
None
MLY  D 884 ( 4.0A)
 0.87A 4kttD-4ngeD:
undetectable		 4kttD-4ngeD:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 GLN D 949
ASP D 951
ILE D 952
ILE D 885
 None
None
None
MLY  D 884 ( 4.0A)
 0.95A 4ndnD-4ngeD:
undetectable		 4ndnD-4ngeD:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 PHE D  88
PHE D 148
LEU D 111
PRO D 122
 None
 1.35A 4o8zA-4ngeD:
undetectable		 4o8zA-4ngeD:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 PHE D 168
HIS D 254
PHE D 169
LEU D 172
 None
None
MLY  D 287 ( 4.5A)
None
 1.44A 4o8zA-4ngeD:
undetectable		 4o8zA-4ngeD:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLN D 486
LEU D 352
LEU D 478
ASN D 481
PHE D 474
 None
 1.46A 4qdcA-4ngeD:
undetectable		 4qdcA-4ngeD:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLY D 101
GLY D 236
THR D 144
LEU D 106
LEU D 245
 None
 1.18A 5bw4A-4ngeD:
undetectable		 5bw4A-4ngeD:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_0
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 GLY D 907
PHE D 138
THR D 139
ASN D 136
HIS D 896
 None
 1.26A 5d0yA-4ngeD:
undetectable		 5d0yA-4ngeD:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ASP D 121
PHE D 123
SER D 958
ASN D 128
 None
 1.13A 5l1fA-4ngeD:
undetectable
5l1fB-4ngeD:
undetectable		 5l1fA-4ngeD:
23.74
5l1fB-4ngeD:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 9 LEU D 467
VAL D  57
LEU D  60
ILE D 451
ALA D  64
 None
 1.35A 5og9A-4ngeD:
undetectable		 5og9A-4ngeD:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 6 LEU D 447
PHE D 443
ASP D  83
HIS D 438
 None
 1.12A 5om3A-4ngeD:
undetectable
5om3B-4ngeD:
undetectable		 5om3A-4ngeD:
7.25
5om3B-4ngeD:
4.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 GLN D 949
ASP D 951
ILE D 952
ILE D 885
 None
None
None
MLY  D 884 ( 4.0A)
 0.94A 5t8sA-4ngeD:
undetectable		 5t8sA-4ngeD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UL4_A_SAMA803_0
(OXSB PROTEIN)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 PHE D 688
ALA D 580
GLY D 775
GLY D 804
GLU D 686
 None
 1.10A 5ul4A-4ngeD:
undetectable		 5ul4A-4ngeD:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 VAL D 701
ARG D 633
TYR D 632
GLU D 367
 None
MLY  D 363 ( 4.1A)
None
MLY  D 363 ( 4.3A)
 1.15A 5umwB-4ngeD:
undetectable
5umwE-4ngeD:
undetectable		 5umwB-4ngeD:
6.20
5umwE-4ngeD:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		5 / 12 VAL D  90
PHE D  92
GLN D 289
PRO D 170
PHE D 169
 None
None
MLY  D 290 ( 4.8A)
None
MLY  D 287 ( 4.5A)
 1.38A 6becA-4ngeD:
undetectable
6becB-4ngeD:
undetectable
6becC-4ngeD:
undetectable		 6becA-4ngeD:
20.75
6becB-4ngeD:
20.75
6becC-4ngeD:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 5 ARG D 924
THR D 139
GLN D 107
ASP D 142
 None
 1.45A 6ectA-4ngeD:
undetectable		 6ectA-4ngeD:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 6 ASP D 377
GLN D 219
ASN D 223
SER D 235
 None
 1.26A 6ekuA-4ngeD:
undetectable		 6ekuA-4ngeD:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ASP D 212
ILE D 216
ARG D 215
ASN D 223
 None
 1.24A 6hisA-4ngeD:
2.4
6hisB-4ngeD:
2.4		 6hisA-4ngeD:
6.05
6hisB-4ngeD:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ASP D 212
ILE D 216
ARG D 215
ASN D 223
 None
 1.23A 6hisB-4ngeD:
2.4
6hisC-4ngeD:
2.4		 6hisB-4ngeD:
6.05
6hisC-4ngeD:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ASP D 212
ILE D 216
ARG D 215
ASN D 223
 None
 1.23A 6hisC-4ngeD:
2.4
6hisD-4ngeD:
2.4		 6hisC-4ngeD:
6.05
6hisD-4ngeD:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ASP D 212
ILE D 216
ARG D 215
ASN D 223
 None
 1.23A 6hisD-4ngeD:
2.2
6hisE-4ngeD:
2.4		 6hisD-4ngeD:
6.05
6hisE-4ngeD:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 8 ASN D 223
ASP D 212
ILE D 216
ARG D 215
 None
 1.24A 6hisA-4ngeD:
2.4
6hisE-4ngeD:
2.4		 6hisA-4ngeD:
6.05
6hisE-4ngeD:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 ARG D 385
HIS D 229
GLU D 386
ASP D 336
 None
 1.31A 6mn4E-4ngeD:
undetectable		 6mn4E-4ngeD:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL
(Homo
sapiens) 		4 / 7 GLU D 634
ASP D 631
CYH D 692
GLU D 695
 None
 0.98A 6mn5E-4ngeD:
undetectable		 6mn5E-4ngeD:
6.56