SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4nh1 CASEIN KINASE II
SUBUNIT BETA
(Homo
sapiens) 		3 / 3 PRO C 121
LEU C 120
HIS C 171
 None
 0.72A 4pevA-4nh1C:
undetectable		 4pevA-4nh1C:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSE_C_HQEC1583_1
(UREASE SUBUNIT ALPHA)		 4nh1 CASEIN KINASE II
SUBUNIT BETA
(Homo
sapiens) 		4 / 5 ILE C  88
GLN C  96
CYH C  23
GLU C  24
 None
 1.28A 5fseC-4nh1C:
undetectable		 5fseC-4nh1C:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4nh1 CASEIN KINASE II
SUBUNIT BETA
(Homo
sapiens) 		5 / 12 ILE C  53
VAL C  25
TRP C   9
PHE C  13
PHE C  22
 None
 1.12A 6hlpA-4nh1C:
undetectable		 6hlpA-4nh1C:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 4nh1 CASEIN KINASE II
SUBUNIT BETA
(Homo
sapiens) 		5 / 12 ILE C  83
VAL C  25
TRP C   9
PHE C  13
PHE C  22
 None
 1.11A 6hlpA-4nh1C:
undetectable		 6hlpA-4nh1C:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4nh1 CASEIN KINASE II
SUBUNIT BETA
(Homo
sapiens) 		4 / 6 TYR C  87
ILE C  88
ALA C  95
ASP C  28
 None
 1.12A 6hu9m-4nh1C:
undetectable
6hu9q-4nh1C:
undetectable		 6hu9m-4nh1C:
16.96
6hu9q-4nh1C:
19.18