SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nha'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4nha ENDORIBONUCLEASE
DICER
(Homo
sapiens) 		5 / 12 LEU A 848
SER A 845
THR A 983
HIS A1031
TYR A 842
 None
 1.22A 1kw0A-4nhaA:
undetectable		 1kw0A-4nhaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 4nha ENDORIBONUCLEASE
DICER
(Homo
sapiens) 		5 / 11 LEU A 848
SER A 845
THR A 983
HIS A1031
TYR A 842
 None
 1.25A 1mmtA-4nhaA:
undetectable		 1mmtA-4nhaA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 4nha ENDORIBONUCLEASE
DICER
(Homo
sapiens) 		4 / 8 ALA A1041
ILE A1033
ILE A 843
TYR A 842
 None
 1.05A 2zmaA-4nhaA:
undetectable		 2zmaA-4nhaA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 4nha ENDORIBONUCLEASE
DICER
(Homo
sapiens) 		5 / 9 ASP A 881
ILE A 882
GLY A 793
ILE A 763
THR A 796
 None
 1.29A 5kr2C-4nhaA:
undetectable		 5kr2C-4nhaA:
16.24