SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nhr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 4nhr LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Escherichia
coli) 		5 / 10 GLY A  45
LEU A  77
LEU A  38
SER A  40
ALA A  50
 None
 1.09A 1pbcA-4nhrA:
undetectable		 1pbcA-4nhrA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4nhr LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Escherichia
coli) 		5 / 12 VAL A  51
VAL A 104
GLY A  78
ALA A 106
LEU A  75
 None
 1.17A 4rrwB-4nhrA:
undetectable		 4rrwB-4nhrA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4nhr LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Escherichia
coli) 		5 / 12 VAL A  51
VAL A 104
GLY A  78
ALA A 106
LEU A  75
 None
 1.17A 4rrzB-4nhrA:
undetectable		 4rrzB-4nhrA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4nhr LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Escherichia
coli) 		4 / 4 LEU A  55
TYR A 116
PRO A  73
ILE A  37
 None
 1.25A 5esgA-4nhrA:
undetectable		 5esgA-4nhrA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 4nhr LPS-ASSEMBLY
LIPOPROTEIN LPTE
(Escherichia
coli) 		5 / 10 VAL A 104
ALA A 120
LEU A  77
LEU A  75
LEU A  47
 None
 0.94A 6f6nA-4nhrA:
1.2
6f6nB-4nhrA:
undetectable		 6f6nA-4nhrA:
18.25
6f6nB-4nhrA:
20.73