SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nic'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4nic DNA-BINDING
TRANSCRIPTIONAL
REGULATOR RSTA
(Klebsiella
pneumoniae) 		4 / 4 ALA A 110
VAL A 107
ALA A 106
HIS A  24
 None
 1.23A 1q23F-4nicA:
undetectable		 1q23F-4nicA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 4nic DNA-BINDING
TRANSCRIPTIONAL
REGULATOR RSTA
(Klebsiella
pneumoniae) 		4 / 8 LEU A  63
ASP A  35
ALA A  37
VAL A  40
 None
 0.81A 4zbqA-4nicA:
undetectable		 4zbqA-4nicA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 4nic DNA-BINDING
TRANSCRIPTIONAL
REGULATOR RSTA
(Klebsiella
pneumoniae) 		4 / 4 VAL A   7
GLU A  31
GLY A  34
LEU A  55
 None
 1.20A 5g5gC-4nicA:
undetectable		 5g5gC-4nicA:
10.37