SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nim'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 4nim VERSICOLORIN
REDUCTASE
(Brucella
melitensis) 		4 / 6 THR A  23
SER A 185
LEU A 186
LEU A 236
 None
 1.00A 4wozA-4nimA:
undetectable
4wozB-4nimA:
2.4		 4wozA-4nimA:
20.29
4wozB-4nimA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 4nim VERSICOLORIN
REDUCTASE
(Brucella
melitensis) 		5 / 12 GLY A  20
SER A  15
LEU A  35
PHE A  27
LEU A   5
 None
 1.17A 5w7pA-4nimA:
6.1		 5w7pA-4nimA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 4nim VERSICOLORIN
REDUCTASE
(Brucella
melitensis) 		5 / 12 LEU A  26
ALA A 230
ILE A  12
ALA A  92
ILE A  88
 None
 1.02A 5xiwD-4nimA:
7.5		 5xiwD-4nimA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 4nim VERSICOLORIN
REDUCTASE
(Brucella
melitensis) 		5 / 12 ASP A  65
ALA A  93
LEU A 123
ARG A 118
LEU A 165
 None
 1.11A 6ew0F-4nimA:
6.4		 6ew0F-4nimA:
15.87