SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nk5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B02_A_C2FA281_0
(PROTEIN (THYMIDYLATE
SYNTHASE))		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		5 / 11 ALA A 196
THR A 194
ILE A  21
LEU A  29
GLY A  14
 NAD  A 300 (-3.1A)
NAD  A 300 (-3.0A)
NAD  A 300 (-3.5A)
None
NAD  A 300 (-3.6A)
 1.10A 1b02A-4nk5A:
undetectable		 1b02A-4nk5A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 6 PHE A  38
ILE A  45
LYS A  50
ALA A  53
 None
 0.99A 1hk2A-4nk5A:
undetectable		 1hk2A-4nk5A:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifA-4nk5A:
5.2		 1kifA-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifB-4nk5A:
5.2		 1kifB-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifC-4nk5A:
5.2		 1kifC-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifD-4nk5A:
5.1		 1kifD-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifE-4nk5A:
5.2		 1kifE-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifF-4nk5A:
5.2		 1kifF-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifG-4nk5A:
5.1		 1kifG-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.13A 1kifH-4nk5A:
5.2		 1kifH-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.14A 1ve9A-4nk5A:
5.2		 1ve9A-4nk5A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.17A 2du8G-4nk5A:
5.1		 2du8G-4nk5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		4 / 5 TYR A 146
TYR A 156
ILE A 200
GLY A 190
 None
 1.18A 2du8J-4nk5A:
4.2		 2du8J-4nk5A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		3 / 3 TYR A 177
GLU A 126
ASP A  68
 None
 0.66A 3bxoA-4nk5A:
5.8		 3bxoA-4nk5A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		3 / 3 TYR A 177
GLU A 126
ASP A  68
 None
 0.61A 3bxoB-4nk5A:
5.3		 3bxoB-4nk5A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_L_TRPL1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		5 / 9 GLY A 226
VAL A  28
ILE A 187
VAL A 247
VAL A 220
 None
 1.50A 3fi0L-4nk5A:
undetectable		 3fi0L-4nk5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		5 / 10 GLY A  10
PHE A  60
LEU A  11
LEU A  86
ILE A  79
 None
 1.23A 3kvrA-4nk5A:
undetectable		 3kvrA-4nk5A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		3 / 3 PRO A  51
LEU A  52
HIS A  19
 None
 0.64A 4pevA-4nk5A:
5.7		 4pevA-4nk5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTR_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 4nk5 ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH]
(Candidatus
Liberibacter
asiaticus) 		5 / 11 GLY A 138
PHE A  88
ILE A 142
ASN A 185
ASP A  87
 None
 1.37A 4rtrA-4nk5A:
3.3		 4rtrA-4nk5A:
25.08