SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 VAL A 488
LEU A 460
VAL A 483
LEU A 467
 None
 0.82A 1cqpA-4nk6A:
undetectable
1cqpB-4nk6A:
undetectable		 1cqpA-4nk6A:
15.35
1cqpB-4nk6A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 LEU A 467
ASN A 430
VAL A 404
GLY A 411
LEU A 475
 None
 1.39A 1fkpA-4nk6A:
undetectable		 1fkpA-4nk6A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 ASP A 331
SER A 357
ILE A 381
GLY A 334
 MLY  A 356 ( 3.7A)
MLY  A 356 ( 4.5A)
None
None
 0.83A 1meiA-4nk6A:
undetectable		 1meiA-4nk6A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 PHE A 194
TRP A 122
GLU A 121
 None
 1.16A 1mogA-4nk6A:
undetectable		 1mogA-4nk6A:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ARG A 447
GLY A 395
GLU A 393
ASN A 397
ILE A 420
 None
 1.43A 1odiA-4nk6A:
undetectable		 1odiA-4nk6A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ARG A 447
GLY A 395
GLU A 393
ASN A 397
ILE A 420
 None
 1.42A 1odiB-4nk6A:
undetectable		 1odiB-4nk6A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ARG A 447
GLY A 395
GLU A 393
ASN A 397
ILE A 420
 None
 1.42A 1odiC-4nk6A:
undetectable		 1odiC-4nk6A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ARG A 447
GLY A 395
GLU A 393
ASN A 397
ILE A 420
 None
 1.38A 1odiD-4nk6A:
undetectable		 1odiD-4nk6A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 ARG A 447
GLY A 395
GLU A 393
ASN A 397
ILE A 420
 None
 1.42A 1odiF-4nk6A:
undetectable		 1odiF-4nk6A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ASN A 359
ASN A 360
ILE A 381
GLY A 364
 None
 0.90A 1oniA-4nk6A:
undetectable
1oniB-4nk6A:
undetectable		 1oniA-4nk6A:
14.52
1oniB-4nk6A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ASN A 359
ASN A 360
ILE A 381
GLY A 364
 None
 0.90A 1oniD-4nk6A:
undetectable
1oniF-4nk6A:
undetectable		 1oniD-4nk6A:
14.52
1oniF-4nk6A:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 THR A 298
VAL A 347
GLY A 279
ILE A 241
TYR A 308
 None
 1.44A 1xvaA-4nk6A:
undetectable		 1xvaA-4nk6A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 303
ILE A 316
GLY A 315
GLY A 292
ILE A 281
 MLY  A 304 ( 3.2A)
None
None
None
None
 0.86A 2avsA-4nk6A:
undetectable		 2avsA-4nk6A:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 303
ILE A 316
GLY A 315
GLY A 292
ILE A 281
 MLY  A 304 ( 3.2A)
None
None
None
None
 0.89A 2avvD-4nk6A:
undetectable		 2avvD-4nk6A:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ASP A 225
GLU A 226
TRP A 290
ARG A 215
 None
 0.82A 2ouzA-4nk6A:
undetectable		 2ouzA-4nk6A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ARG A 186
GLU A 213
GLN A 189
PRO A 229
 None
MLY  A 191 ( 4.8A)
None
None
 1.32A 2qqtA-4nk6A:
undetectable		 2qqtA-4nk6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 303
ILE A 316
GLY A 315
GLY A 292
ILE A 281
 MLY  A 304 ( 3.2A)
None
None
None
None
 0.95A 2r5pA-4nk6A:
undetectable		 2r5pA-4nk6A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 303
ILE A 316
GLY A 315
GLY A 292
ILE A 281
 MLY  A 304 ( 3.2A)
None
None
None
None
 0.94A 2r5pC-4nk6A:
undetectable		 2r5pC-4nk6A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 VAL A 303
TRP A 240
TRP A 280
 MLY  A 304 ( 3.2A)
MLY  A  89 ( 3.7A)
MLY  A  89 ( 4.8A)
 1.39A 2xdcA-4nk6A:
undetectable
2xdcB-4nk6A:
undetectable		 2xdcA-4nk6A:
3.34
2xdcB-4nk6A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 TRP A 280
VAL A 303
TRP A 240
 MLY  A  89 ( 4.8A)
MLY  A 304 ( 3.2A)
MLY  A  89 ( 3.7A)
 1.40A 2xdcA-4nk6A:
undetectable
2xdcB-4nk6A:
undetectable		 2xdcA-4nk6A:
3.34
2xdcB-4nk6A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 VAL A 303
TRP A 240
TRP A 280
 MLY  A 304 ( 3.2A)
MLY  A  89 ( 3.7A)
MLY  A  89 ( 4.8A)
 1.01A 2xdcC-4nk6A:
undetectable
2xdcD-4nk6A:
undetectable		 2xdcC-4nk6A:
3.34
2xdcD-4nk6A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 VAL A 303
TRP A 240
TRP A 280
 MLY  A 304 ( 3.2A)
MLY  A  89 ( 3.7A)
MLY  A  89 ( 4.8A)
 1.39A 2y5mA-4nk6A:
undetectable
2y5mB-4nk6A:
undetectable		 2y5mA-4nk6A:
3.34
2y5mB-4nk6A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 VAL A 303
TRP A 240
TRP A 280
 MLY  A 304 ( 3.2A)
MLY  A  89 ( 3.7A)
MLY  A  89 ( 4.8A)
 1.38A 2y6nA-4nk6A:
undetectable
2y6nB-4nk6A:
undetectable		 2y6nA-4nk6A:
3.34
2y6nB-4nk6A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 TRP A 280
VAL A 303
TRP A 240
 MLY  A  89 ( 4.8A)
MLY  A 304 ( 3.2A)
MLY  A  89 ( 3.7A)
 1.38A 2y6nA-4nk6A:
undetectable
2y6nB-4nk6A:
undetectable		 2y6nA-4nk6A:
3.34
2y6nB-4nk6A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 TYR A 291
PHE A 293
GLY A 315
VAL A 303
PHE A 301
 None
None
None
MLY  A 304 ( 3.2A)
None
 1.20A 2zznA-4nk6A:
undetectable		 2zznA-4nk6A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_A_C2FA401_0
(AMINOMETHYLTRANSFERA
SE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 MET A 249
ILE A 195
VAL A 231
MET A 246
PHE A 176
 None
 1.48A 3a8iA-4nk6A:
undetectable		 3a8iA-4nk6A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCL_A_AINA609_1
(LACTOPEROXIDASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 6 ARG A 186
GLU A 213
GLN A 189
PRO A 229
 None
MLY  A 191 ( 4.8A)
None
None
 1.30A 3gclA-4nk6A:
undetectable		 3gclA-4nk6A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 LEU A 467
ASN A 430
VAL A 404
GLY A 411
LEU A 475
 None
 1.38A 3lp1A-4nk6A:
undetectable		 3lp1A-4nk6A:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 TYR A 294
VAL A 376
VAL A 347
ILE A 327
 None
 1.18A 3ms9B-4nk6A:
undetectable		 3ms9B-4nk6A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B520_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 HIS A 339
LEU A 391
ARG A 413
ILE A 381
LEU A 399
 MLY  A 338 ( 4.2A)
None
None
None
None
 1.07A 3nrrB-4nk6A:
undetectable		 3nrrB-4nk6A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA309_1
(BETA-LACTAMASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 ILE A 342
ARG A 413
THR A 390
GLU A 393
 None
 1.49A 3ny4A-4nk6A:
undetectable		 3ny4A-4nk6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 VAL A 196
GLU A 276
LYS A 111
PHE A 112
 None
None
MLY  A 110 ( 2.9A)
None
 1.33A 3rv5C-4nk6A:
undetectable
3rv5D-4nk6A:
undetectable		 3rv5C-4nk6A:
11.34
3rv5D-4nk6A:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 411
GLY A 388
LEU A 432
ALA A 427
ASN A 470
 None
 1.28A 3sxjA-4nk6A:
undetectable		 3sxjA-4nk6A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 GLY A 411
GLY A 388
LEU A 432
ALA A 427
ASN A 470
 None
 1.28A 3sxjB-4nk6A:
undetectable		 3sxjB-4nk6A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 VAL A 303
TRP A 240
TRP A 280
 MLY  A 304 ( 3.2A)
MLY  A  89 ( 3.7A)
MLY  A  89 ( 4.8A)
 1.05A 3zq8A-4nk6A:
undetectable
3zq8B-4nk6A:
undetectable		 3zq8A-4nk6A:
3.34
3zq8B-4nk6A:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 5 PHE A 293
PHE A 301
ILE A 281
THR A 239
 None
 0.91A 4ejjC-4nk6A:
undetectable		 4ejjC-4nk6A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		3 / 3 TRP A 234
GLN A 238
THR A 233
 None
MLY  A 200 ( 3.7A)
None
 0.77A 4m2xA-4nk6A:
undetectable		 4m2xA-4nk6A:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 8 LEU A 399
VAL A 414
VAL A 435
LEU A 367
 None
 1.15A 4q0bA-4nk6A:
undetectable		 4q0bA-4nk6A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 231
LEU A 145
ILE A 168
ILE A 178
MET A 201
 None
 1.23A 4y0pA-4nk6A:
undetectable		 4y0pA-4nk6A:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 SER A 394
GLY A 388
SER A 363
ILE A 412
ALA A 427
 None
 1.37A 5entC-4nk6A:
undetectable		 5entC-4nk6A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 9 ALA A 287
ASP A 288
ILE A 312
GLY A 292
ILE A 316
 None
MLY  A 336 ( 4.8A)
MLY  A 336 ( 4.9A)
None
None
 1.29A 5kr2A-4nk6A:
undetectable		 5kr2A-4nk6A:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_2
(CYTOCHROME P450 3A4)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 ILE A 352
PHE A 293
THR A 298
THR A 335
 None
None
None
MLY  A 336 ( 3.9A)
 1.04A 5vc0A-4nk6A:
undetectable		 5vc0A-4nk6A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ASN A 306
GLY A 305
MET A 246
VAL A 231
ILE A 241
 MLY  A 304 ( 3.4A)
MLY  A 304 ( 2.4A)
None
None
None
 1.11A 5vooD-4nk6A:
undetectable		 5vooD-4nk6A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 VAL A 259
PRO A  76
PHE A 353
PRO A 318
ILE A 352
 None
 1.46A 6becA-4nk6A:
undetectable
6becB-4nk6A:
undetectable
6becC-4nk6A:
undetectable		 6becA-4nk6A:
21.06
6becB-4nk6A:
21.06
6becC-4nk6A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ILE A 281
ASN A 311
PHE A 286
GLY A 258
ILE A 203
 None
 1.11A 6dwnD-4nk6A:
undetectable		 6dwnD-4nk6A:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4nk6 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE
(Pseudomonas
syringae
group
genomosp.
3) 		4 / 7 HIS A 339
ARG A 369
ASP A 368
GLU A 393
 MLY  A 338 ( 4.2A)
None
None
None
 1.36A 6mn4F-4nk6A:
undetectable		 6mn4F-4nk6A:
20.37