SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nkb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 4nkb PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE ZYG-1
(Caenorhabditis
elegans) 		5 / 11 ILE A 506
MET A 501
ASP A 502
GLY A 462
TYR A 532
 None
 1.16A 2azyA-4nkbA:
undetectable		 2azyA-4nkbA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 4nkb PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE ZYG-1
(Caenorhabditis
elegans) 		4 / 6 GLN A 540
LEU A 535
GLU A 539
LEU A 482
 None
 0.89A 3h5gA-4nkbA:
undetectable
3h5gC-4nkbA:
undetectable		 3h5gA-4nkbA:
7.11
3h5gC-4nkbA:
7.11