SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nkj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4nkj HEMAGGLUTININ HA2
(Influenza
B
virus) 		3 / 3 ASP A  56
ASP A  51
ASN A 115
 None
 0.83A 2bm9D-4nkjA:
undetectable		 2bm9D-4nkjA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 4nkj HEMAGGLUTININ HA2
(Influenza
B
virus) 		4 / 7 GLY A  38
ALA A  39
MET A  40
LEU A  43
 None
 0.47A 2wekB-4nkjA:
undetectable		 2wekB-4nkjA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 4nkj HEMAGGLUTININ HA2
(Influenza
B
virus) 		3 / 3 ARG A  35
GLU A  42
ASP A 120
 None
 0.86A 3g2oA-4nkjA:
undetectable		 3g2oA-4nkjA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 4nkj HEMAGGLUTININ HA2
(Influenza
B
virus) 		5 / 12 LEU A  85
GLY A  76
GLY A 106
PHE A 108
ILE A  66
 None
 1.20A 5tuiB-4nkjA:
undetectable		 5tuiB-4nkjA:
19.95