SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nlm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		3 / 3 ALA A 178
VAL A 177
GLN A 208
 None
 0.50A 3of4B-4nlmA:
undetectable		 3of4B-4nlmA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 9 ILE A 236
GLN A 225
ALA A 227
LEU A 234
ALA A 261
 None
 1.03A 3ozvB-4nlmA:
undetectable		 3ozvB-4nlmA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		4 / 7 TYR A 302
GLN A 324
TYR A 274
PHE A 271
 None
 1.35A 4grqA-4nlmA:
undetectable
4grqC-4nlmA:
undetectable		 4grqA-4nlmA:
15.19
4grqC-4nlmA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		4 / 5 PHE A 257
PHE A 248
LEU A 244
PRO A 273
 None
 1.40A 4o8zA-4nlmA:
undetectable		 4o8zA-4nlmA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.33A 4qvlV-4nlmA:
0.2
4qvlW-4nlmA:
0.0		 4qvlV-4nlmA:
19.11
4qvlW-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.33A 4qvmH-4nlmA:
0.2
4qvmI-4nlmA:
0.0		 4qvmH-4nlmA:
19.11
4qvmI-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.33A 4qvmV-4nlmA:
0.2
4qvmW-4nlmA:
0.0		 4qvmV-4nlmA:
19.11
4qvmW-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.35A 4qvnH-4nlmA:
undetectable
4qvnI-4nlmA:
undetectable		 4qvnH-4nlmA:
19.11
4qvnI-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.35A 4qvnV-4nlmA:
undetectable
4qvnW-4nlmA:
undetectable		 4qvnV-4nlmA:
19.11
4qvnW-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.34A 4qvqH-4nlmA:
undetectable
4qvqI-4nlmA:
undetectable		 4qvqH-4nlmA:
19.11
4qvqI-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.34A 4qvqV-4nlmA:
undetectable
4qvqW-4nlmA:
undetectable		 4qvqV-4nlmA:
19.11
4qvqW-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.31A 4qvwH-4nlmA:
0.2
4qvwI-4nlmA:
0.0		 4qvwH-4nlmA:
19.11
4qvwI-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.31A 4qvwV-4nlmA:
0.2
4qvwW-4nlmA:
0.0		 4qvwV-4nlmA:
19.11
4qvwW-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 10 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.31A 4qw3H-4nlmA:
undetectable
4qw3I-4nlmA:
undetectable		 4qw3H-4nlmA:
19.11
4qw3I-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.30A 4qw3V-4nlmA:
undetectable
4qw3W-4nlmA:
undetectable		 4qw3V-4nlmA:
19.11
4qw3W-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.34A 4qwuH-4nlmA:
undetectable
4qwuI-4nlmA:
undetectable		 4qwuH-4nlmA:
19.11
4qwuI-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.34A 4qwuV-4nlmA:
undetectable
4qwuW-4nlmA:
undetectable		 4qwuV-4nlmA:
19.11
4qwuW-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 11 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.34A 5cz7H-4nlmA:
0.2
5cz7I-4nlmA:
0.0		 5cz7H-4nlmA:
19.11
5cz7I-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		5 / 12 THR A 137
SER A  92
THR A 115
ALA A 114
THR A 132
 None
 1.32A 5d0xH-4nlmA:
undetectable
5d0xI-4nlmA:
undetectable		 5d0xH-4nlmA:
19.11
5d0xI-4nlmA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		4 / 5 PHE A  47
GLY A  52
ASP A 342
ILE A 356
 None
 1.01A 5ik1A-4nlmA:
undetectable		 5ik1A-4nlmA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMD_C_6UBC1304_1
(ION TRANSPORT
PROTEIN)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		4 / 5 TYR A 206
ILE A 219
LEU A 202
GLY A 203
 None
 0.66A 5kmdC-4nlmA:
undetectable
5kmdD-4nlmA:
undetectable		 5kmdC-4nlmA:
23.36
5kmdD-4nlmA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 4nlm LMO1340 PROTEIN
(Listeria
monocytogenes) 		4 / 6 GLU A 201
LEU A 202
LYS A 238
LEU A 244
 None
 1.19A 5yvnA-4nlmA:
undetectable		 5yvnA-4nlmA:
21.69