SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		3 / 3 ASP A 110
PHE A  54
ARG A 112
 None
 0.84A 2a3aA-4nmiA:
undetectable		 2a3aA-4nmiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_B_CFFB2434_1
(CHITINASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 6 TYR A 103
ASP A 110
PHE A  55
ARG A 112
 None
 1.44A 2a3bB-4nmiA:
undetectable		 2a3bB-4nmiA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		5 / 11 ILE A  94
ASN A 261
SER A 167
ILE A 168
ILE A 132
 None
 1.19A 2blaA-4nmiA:
undetectable		 2blaA-4nmiA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_B_ACHB1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 8 TYR A   5
SER A 186
ILE A  15
SER A 147
 None
 0.84A 2xz5B-4nmiA:
undetectable
2xz5E-4nmiA:
undetectable		 2xz5B-4nmiA:
22.05
2xz5E-4nmiA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 4nmi ECTD
(Virgibacillus
salexigens) 		3 / 3 GLU A 150
VAL A 213
CYH A 193
 None
 1.06A 3fbxA-4nmiA:
undetectable		 3fbxA-4nmiA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 5 GLN A  99
ASP A 100
HIS A  96
GLU A 291
 None
 1.03A 3r4xA-4nmiA:
undetectable		 3r4xA-4nmiA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 5 GLN A  99
ASP A 100
HIS A  96
GLU A 291
 None
 1.02A 3r55A-4nmiA:
undetectable		 3r55A-4nmiA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 7 ASN A 261
ASP A 148
HIS A 146
HIS A 248
 None
 1.01A 3t01A-4nmiA:
undetectable		 3t01A-4nmiA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 6 GLU A  87
ARG A  92
GLU A  85
SER A  88
 None
 1.12A 4kr3A-4nmiA:
undetectable		 4kr3A-4nmiA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 6 GLN A  99
ASP A 100
HIS A  96
GLU A 291
 None
 0.99A 4qyqC-4nmiA:
undetectable		 4qyqC-4nmiA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 6 GLN A  99
ASP A 100
HIS A  96
GLU A 291
 None
 0.99A 5hpwC-4nmiA:
undetectable		 5hpwC-4nmiA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 4nmi ECTD
(Virgibacillus
salexigens) 		4 / 6 ARG A  18
GLY A  47
THR A 246
SER A 244
 None
 1.10A 5ny7A-4nmiA:
undetectable		 5ny7A-4nmiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 4nmi ECTD
(Virgibacillus
salexigens) 		3 / 3 TYR A   5
HIS A 153
PHE A 149
 None
 1.02A 6esmA-4nmiA:
undetectable		 6esmA-4nmiA:
14.04