SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nnm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M4I_A_KANA500_1 (AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERA SE)	4nnm	TAX1-BINDING PROTEIN 3 (Homo sapiens)	4 / 8	ASP A 41 GLY A 35 SER A 48 ASP A 50	None	0.86A	1m4iA-4nnmA: undetectable	1m4iA-4nnmA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_A_SAMA301_1 (HEMK PROTEIN)	4nnm	TAX1-BINDING PROTEIN 3 (Homo sapiens)	4 / 4	THR A 59 GLY A 37 ASP A 39 ALA A 94	None	1.23A	1sg9A-4nnmA: undetectable	1sg9A-4nnmA: 16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IDW_B_017B401_2 (PROTEASE)	4nnm	TAX1-BINDING PROTEIN 3 (Homo sapiens)	5 / 9	LEU A 108 GLY A 71 ALA A 70 GLY A 65 ILE A 19	None	0.94A	2idwB-4nnmA: undetectable	2idwB-4nnmA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXV_C_478C200_1 (HIV-1 PROTEASE)	4nnm	TAX1-BINDING PROTEIN 3 (Homo sapiens)	5 / 9	LEU A 108 GLY A 71 ALA A 70 GLY A 65 ILE A 19	None	0.92A	3oxvC-4nnmA: undetectable	3oxvC-4nnmA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RVJ_B_478B101_2 (HIV-1 PROTEASE)	4nnm	TAX1-BINDING PROTEIN 3 (Homo sapiens)	5 / 9	LEU A 108 GLY A 71 ALA A 70 GLY A 65 ILE A 19	None	0.93A	4rvjB-4nnmA: undetectable	4rvjB-4nnmA: 19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RVJ_D_478D101_2 (HIV-1 PROTEASE)	4nnm	TAX1-BINDING PROTEIN 3 (Homo sapiens)	5 / 9	LEU A 108 GLY A 71 ALA A 70 GLY A 65 ILE A 19	None	0.93A	4rvjD-4nnmA: undetectable	4rvjD-4nnmA: 19.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1M4I_A_KANA500_1","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","4nnm","TAX1-BINDING PROTEIN 3","Homo sapiens",4,"ASP A  41;GLY A  35;SER A  48;ASP A  50","None","0.86A","1m4iA-4nnmA:undetectable","1m4iA-4nnmA:16.67"],["1SG9_A_SAMA301_1","HEMK PROTEIN","4nnm","TAX1-BINDING PROTEIN 3","Homo sapiens",4,"THR A  59;GLY A  37;ASP A  39;ALA A  94","None","1.23A","1sg9A-4nnmA:undetectable","1sg9A-4nnmA:16.30"],["2IDW_B_017B401_2","PROTEASE","4nnm","TAX1-BINDING PROTEIN 3","Homo sapiens",5,"LEU A 108;GLY A  71;ALA A  70;GLY A  65;ILE A  19","None","0.94A","2idwB-4nnmA:undetectable","2idwB-4nnmA:18.80"],["3OXV_C_478C200_1","HIV-1 PROTEASE","4nnm","TAX1-BINDING PROTEIN 3","Homo sapiens",5,"LEU A 108;GLY A  71;ALA A  70;GLY A  65;ILE A  19","None","0.92A","3oxvC-4nnmA:undetectable","3oxvC-4nnmA:19.30"],["4RVJ_B_478B101_2","HIV-1 PROTEASE","4nnm","TAX1-BINDING PROTEIN 3","Homo sapiens",5,"LEU A 108;GLY A  71;ALA A  70;GLY A  65;ILE A  19","None","0.93A","4rvjB-4nnmA:undetectable","4rvjB-4nnmA:19.30"],["4RVJ_D_478D101_2","HIV-1 PROTEASE","4nnm","TAX1-BINDING PROTEIN 3","Homo sapiens",5,"LEU A 108;GLY A  71;ALA A  70;GLY A  65;ILE A  19","None","0.93A","4rvjD-4nnmA:undetectable","4rvjD-4nnmA:19.30"]]