SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nnr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 9 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.35A 1bkfA-4nnrA:
16.1		 1bkfA-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1C9H_A_RAPA108_1
(FKBP12.6)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.49A 1c9hA-4nnrA:
15.6		 1c9hA-4nnrA:
35.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.40A 1fapA-4nnrA:
16.6		 1fapA-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 12 TYR A  56
PHE A  76
VAL A  85
TRP A  89
ILE A 121
 FK5  A 201 (-4.1A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.5A)
None
 1.03A 1fapA-4nnrA:
16.6		 1fapA-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.31A 1fkbA-4nnrA:
16.5		 1fkbA-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 12 TYR A  56
PHE A  76
VAL A  85
TRP A  89
ILE A 121
 FK5  A 201 (-4.1A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.5A)
None
 1.06A 1fkbA-4nnrA:
16.5		 1fkbA-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKF_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.29A 1fkfA-4nnrA:
16.2		 1fkfA-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKJ_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.32A 1fkjA-4nnrA:
16.2		 1fkjA-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FKL_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.36A 1fklA-4nnrA:
16.5		 1fklA-4nnrA:
39.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
GLY A  83
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
None
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.28A 1pbkA-4nnrA:
15.6		 1pbkA-4nnrA:
38.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PBK_A_RAPA225_1
(FKBP25)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		7 / 12 TYR A  56
GLY A  83
VAL A  85
TRP A  89
ALA A 117
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
None
FK5  A 201 (-3.4A)
FK5  A 201 (-3.5A)
FK5  A 201 ( 4.6A)
None
FK5  A 201 (-4.9A)
 1.13A 1pbkA-4nnrA:
15.6		 1pbkA-4nnrA:
38.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 9 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.37A 1q6iA-4nnrA:
13.5		 1q6iA-4nnrA:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_B_FK5B401_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.34A 1q6iB-4nnrA:
13.4		 1q6iB-4nnrA:
27.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TCO_C_FK5C509_2
(FK506-BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.34A 1tcoC-4nnrA:
16.1		 1tcoC-4nnrA:
39.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.18A 1yatA-4nnrA:
16.6		 1yatA-4nnrA:
40.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG3_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.39A 2dg3A-4nnrA:
16.2		 2dg3A-4nnrA:
40.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG4_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		7 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.40A 2dg4A-4nnrA:
15.7		 2dg4A-4nnrA:
39.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		7 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.43A 2dg9A-4nnrA:
15.9		 2dg9A-4nnrA:
39.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FKE_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.29A 2fkeA-4nnrA:
16.3		 2fkeA-4nnrA:
40.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 11 PHE A  66
ASP A  67
VAL A  85
ILE A  86
TRP A  89
 FK5  A 201 (-4.7A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
 0.66A 2vcdA-4nnrA:
10.6		 2vcdA-4nnrA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 11 PHE A  66
VAL A  85
ILE A  86
TRP A  89
TYR A 112
 FK5  A 201 (-4.7A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
 0.94A 2vcdA-4nnrA:
10.6		 2vcdA-4nnrA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
 0.75A 2vcdA-4nnrA:
10.6		 2vcdA-4nnrA:
30.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCD_A_RAPA138_1
(OUTER MEMBRANE
PROTEIN MIP)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 11 TYR A  56
VAL A  85
ILE A  86
TRP A  89
TYR A 112
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
 0.62A 2vcdA-4nnrA:
10.6		 2vcdA-4nnrA:
30.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
PHE A  66
ASP A  67
PHE A  76
VAL A  85
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-4.7A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.28A 2vn1A-4nnrA:
16.1		 2vn1A-4nnrA:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VN1_B_FK5B501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.24A 2vn1B-4nnrA:
15.9		 2vn1B-4nnrA:
38.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_1
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.28A 3ihzA-4nnrA:
15.7		 3ihzA-4nnrA:
39.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IHZ_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE, PUTATIVE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 8 TYR A  56
PHE A  76
TRP A  89
TYR A 112
ILE A 121
 FK5  A 201 (-4.1A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
 0.40A 3ihzB-4nnrA:
15.5		 3ihzB-4nnrA:
39.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KZ7_A_RAPA225_1
(FK506-BINDING
PROTEIN 3)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.25A 3kz7A-4nnrA:
15.4		 3kz7A-4nnrA:
45.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3O5R_A_FK5A1001_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		10 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
LYS A 120
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-3.5A)
None
FK5  A 201 (-4.9A)
 0.58A 3o5rA-4nnrA:
15.7		 3o5rA-4nnrA:
43.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UF8_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.26A 3uf8A-4nnrA:
16.4		 3uf8A-4nnrA:
34.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQA_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.26A 3uqaA-4nnrA:
16.5		 3uqaA-4nnrA:
34.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 8 TYR A  56
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.31A 3uqbA-4nnrA:
16.0		 3uqbA-4nnrA:
33.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VAW_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN
SMT3,PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		10 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ARG A 115
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.2A)
None
FK5  A 201 (-4.9A)
 0.60A 3vawA-4nnrA:
13.2		 3vawA-4nnrA:
34.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		10 / 12 TYR A  56
ASP A  67
GLN A  84
VAL A  85
ILE A  86
TRP A  89
TYR A 112
LYS A 120
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
None
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-3.5A)
None
FK5  A 201 (-4.9A)
 0.64A 4drhA-4nnrA:
14.7		 4drhA-4nnrA:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		10 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
LYS A 120
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-3.5A)
None
FK5  A 201 (-4.9A)
 0.53A 4drhA-4nnrA:
14.7		 4drhA-4nnrA:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRH_D_RAPD201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		10 / 12 TYR A  56
ASP A  67
PHE A  76
GLN A  84
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
None
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.57A 4drhD-4nnrA:
14.4		 4drhD-4nnrA:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
GLN A  84
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
None
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.60A 4driA-4nnrA:
16.2		 4driA-4nnrA:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRI_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP5)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.36A 4driA-4nnrA:
16.2		 4driA-4nnrA:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DRJ_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		10 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
LYS A 120
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-3.5A)
None
FK5  A 201 (-4.9A)
 0.43A 4drjA-4nnrA:
16.1		 4drjA-4nnrA:
40.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.21A 4dz2A-4nnrA:
16.3
4dz2B-4nnrA:
16.4		 4dz2A-4nnrA:
44.78
4dz2B-4nnrA:
44.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.23A 4dz2A-4nnrA:
16.3
4dz2B-4nnrA:
16.4		 4dz2A-4nnrA:
44.78
4dz2B-4nnrA:
44.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.19A 4dz3A-4nnrA:
16.6		 4dz3A-4nnrA:
45.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.22A 4dz3B-4nnrA:
16.6		 4dz3B-4nnrA:
45.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LAX_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		10 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
LYS A 120
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-3.5A)
None
FK5  A 201 (-4.9A)
 0.49A 4laxA-4nnrA:
16.2		 4laxA-4nnrA:
32.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 10 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.35A 4odoA-4nnrA:
13.2		 4odoA-4nnrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 10 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.33A 4odoB-4nnrA:
12.9		 4odoB-4nnrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 10 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.36A 4odoC-4nnrA:
12.9		 4odoC-4nnrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		6 / 12 TYR A  56
ASP A  67
ILE A  86
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.36A 4odrA-4nnrA:
15.1
4odrB-4nnrA:
14.9		 4odrA-4nnrA:
28.47
4odrB-4nnrA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 11 TYR A  56
ASP A  67
ILE A  86
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.30A 4odrA-4nnrA:
15.1
4odrB-4nnrA:
14.9		 4odrA-4nnrA:
28.47
4odrB-4nnrA:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		5 / 12 GLY A  99
LEU A 134
MET A  54
VAL A 131
ILE A 136
 None
 1.35A 4okbA-4nnrA:
undetectable		 4okbA-4nnrA:
18.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT2_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.35A 4qt2A-4nnrA:
16.0		 4qt2A-4nnrA:
39.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QT3_A_RAPA202_1
(FK506-BINDING
PROTEIN (FKBP)-TYPE
PEPTIDYL-PROPYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.43A 4qt3A-4nnrA:
14.9		 4qt3A-4nnrA:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5B8I_C_FK5C201_3
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.34A 5b8iC-4nnrA:
15.6		 5b8iC-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.30A 5d75A-4nnrA:
15.9		 5d75A-4nnrA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GPG_A_RAPA301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.20A 5gpgA-4nnrA:
16.3		 5gpgA-4nnrA:
44.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HKG_A_RAPA201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1B)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.44A 5hkgA-4nnrA:
15.7		 5hkgA-4nnrA:
35.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.16A 5huaA-4nnrA:
16.7		 5huaA-4nnrA:
46.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
 0.47A 5hw8A-4nnrA:
15.6
5hw8D-4nnrA:
15.5		 5hw8A-4nnrA:
36.00
5hw8D-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_B_FK5B201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.37A 5hw8B-4nnrA:
15.4		 5hw8B-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 10 TYR A  56
ASP A  67
VAL A  85
ILE A  86
TRP A  89
TYR A 112
LEU A 127
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.31A 5hw8C-4nnrA:
15.3
5hw8H-4nnrA:
13.7		 5hw8C-4nnrA:
36.00
5hw8H-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.40A 5hw8D-4nnrA:
15.5		 5hw8D-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_E_FK5E201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.37A 5hw8E-4nnrA:
15.2		 5hw8E-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		8 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
FK5  A 201 (-4.9A)
 0.40A 5hw8B-4nnrA:
15.4
5hw8F-4nnrA:
13.1
5hw8G-4nnrA:
15.0		 5hw8B-4nnrA:
36.00
5hw8F-4nnrA:
36.00
5hw8G-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_G_FK5G201_2
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.41A 5hw8G-4nnrA:
15.0		 5hw8G-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		7 / 8 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.9A)
 0.58A 5hw8H-4nnrA:
13.7		 5hw8H-4nnrA:
36.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5HWC_A_FK5A201_1
(FK506-BINDING
PROTEIN 1A)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 11 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.23A 5hwcA-4nnrA:
16.3		 5hwcA-4nnrA:
43.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.35A 6mkeA-4nnrA:
15.5
6mkeD-4nnrA:
15.7		 6mkeA-4nnrA:
38.89
6mkeD-4nnrA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 12 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.30A 6mkeB-4nnrA:
15.6
6mkeC-4nnrA:
15.7		 6mkeB-4nnrA:
38.89
6mkeC-4nnrA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.28A 6mkeC-4nnrA:
15.7		 6mkeC-4nnrA:
38.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MKE_D_FK5D201_1
(PEPTIDYLPROLYL
ISOMERASE)		 4nnr PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2
(Homo
sapiens) 		9 / 10 TYR A  56
ASP A  67
PHE A  76
VAL A  85
ILE A  86
TRP A  89
TYR A 112
ILE A 121
PHE A 129
 FK5  A 201 (-4.1A)
FK5  A 201 (-3.4A)
FK5  A 201 (-4.0A)
FK5  A 201 (-3.4A)
FK5  A 201 (-3.8A)
FK5  A 201 (-3.5A)
FK5  A 201 (-4.5A)
None
FK5  A 201 (-4.9A)
 0.28A 6mkeD-4nnrA:
15.7		 6mkeD-4nnrA:
38.89