SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nnu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S8F_B_BEZB1503_0 (RAS-RELATED PROTEIN RAB-9A)	4nnu	TRANSCRIPTION FACTOR A, MITOCHONDRIAL (Homo sapiens)	4 / 6	VAL A 185 THR A 184 GLU A 180 LEU A 182	None	1.11A	1s8fB-4nnuA: undetectable	1s8fB-4nnuA: 18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DV1_A_SRYA1601_1 (16S RRNA RIBOSOMAL PROTEIN S12)	4nnu	TRANSCRIPTION FACTOR A, MITOCHONDRIAL (Homo sapiens)	3 / 3	LYS A 52 LYS A 51 PRO A 50	None	1.06A	4dv1L-4nnuA: undetectable	4dv1L-4nnuA: 18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZC_A_ACTA401_0 (PROTON-GATED ION CHANNEL)	4nnu	TRANSCRIPTION FACTOR A, MITOCHONDRIAL (Homo sapiens)	4 / 6	ILE A 84 PHE A 60 ILE A 67 GLU A 63	None	1.23A	4zzcA-4nnuA: undetectable 4zzcB-4nnuA: undetectable	4zzcA-4nnuA: 19.63 4zzcB-4nnuA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZC_B_ACTB401_0 (PROTON-GATED ION CHANNEL)	4nnu	TRANSCRIPTION FACTOR A, MITOCHONDRIAL (Homo sapiens)	4 / 6	ILE A 84 PHE A 60 ILE A 67 GLU A 63	None	1.24A	4zzcB-4nnuA: undetectable 4zzcC-4nnuA: undetectable	4zzcB-4nnuA: 19.63 4zzcC-4nnuA: 19.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S8F_B_BEZB1503_0","RAS-RELATED PROTEIN RAB-9A","4nnu","TRANSCRIPTION FACTOR A, MITOCHONDRIAL","Homo sapiens",4,"VAL A 185;THR A 184;GLU A 180;LEU A 182","None","1.11A","1s8fB-4nnuA:undetectable","1s8fB-4nnuA:18.80"],["4DV1_A_SRYA1601_1","16S RRNA;RIBOSOMAL PROTEIN S12","4nnu","TRANSCRIPTION FACTOR A, MITOCHONDRIAL","Homo sapiens",3,"LYS A  52;LYS A  51;PRO A  50","None","1.06A","4dv1L-4nnuA:undetectable","4dv1L-4nnuA:18.37"],["4ZZC_A_ACTA401_0","PROTON-GATED ION CHANNEL","4nnu","TRANSCRIPTION FACTOR A, MITOCHONDRIAL","Homo sapiens",4,"ILE A  84;PHE A  60;ILE A  67;GLU A  63","None","1.23A","4zzcA-4nnuA:undetectable;4zzcB-4nnuA:undetectable","4zzcA-4nnuA:19.63;4zzcB-4nnuA:19.63"],["4ZZC_B_ACTB401_0","PROTON-GATED ION CHANNEL","4nnu","TRANSCRIPTION FACTOR A, MITOCHONDRIAL","Homo sapiens",4,"ILE A  84;PHE A  60;ILE A  67;GLU A  63","None","1.24A","4zzcB-4nnuA:undetectable;4zzcC-4nnuA:undetectable","4zzcB-4nnuA:19.63;4zzcC-4nnuA:19.63"]]