SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nob'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 5 TYR A  54
ILE A  95
ARG A  52
GLY A 113
 None
 1.34A 2du8G-4nobA:
undetectable		 2du8G-4nobA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 7 SER A  29
VAL A 127
ARG A  57
GLU A 126
 None
None
EDO  A 204 (-4.0A)
MG  A 202 (-2.6A)
 1.38A 3n5tA-4nobA:
undetectable
3n5tB-4nobA:
undetectable		 3n5tA-4nobA:
15.72
3n5tB-4nobA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 6 ILE A  95
LEU A  84
ARG A  57
THR A  65
 None
None
EDO  A 204 (-4.0A)
None
 0.96A 3wg7A-4nobA:
undetectable
3wg7J-4nobA:
undetectable		 3wg7A-4nobA:
12.43
3wg7J-4nobA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 7 GLU A 126
SER A  29
VAL A 127
ARG A  57
 MG  A 202 (-2.6A)
None
None
EDO  A 204 (-4.0A)
 1.44A 5adlA-4nobA:
undetectable
5adlB-4nobA:
undetectable		 5adlA-4nobA:
15.72
5adlB-4nobA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 7 GLU A 126
SER A  29
VAL A 127
ARG A  57
 MG  A 202 (-2.6A)
None
None
EDO  A 204 (-4.0A)
 1.41A 5fj3A-4nobA:
undetectable
5fj3B-4nobA:
undetectable		 5fj3A-4nobA:
15.72
5fj3B-4nobA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 7 GLU A 126
SER A  29
VAL A 127
ARG A  57
 MG  A 202 (-2.6A)
None
None
EDO  A 204 (-4.0A)
 1.45A 5vv7A-4nobA:
undetectable
5vv7B-4nobA:
undetectable		 5vv7A-4nobA:
15.72
5vv7B-4nobA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 7 GLU A 126
SER A  29
VAL A 127
ARG A  57
 MG  A 202 (-2.6A)
None
None
EDO  A 204 (-4.0A)
 1.43A 5vvnA-4nobA:
undetectable
5vvnB-4nobA:
undetectable		 5vvnA-4nobA:
15.72
5vvnB-4nobA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 8 ILE A  95
LEU A  84
ARG A  57
THR A  65
 None
None
EDO  A 204 (-4.0A)
None
 0.82A 5zcoA-4nobA:
undetectable
5zcoJ-4nobA:
undetectable		 5zcoA-4nobA:
12.43
5zcoJ-4nobA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 7 SER A  29
VAL A 127
ARG A  57
GLU A 126
 None
None
EDO  A 204 (-4.0A)
MG  A 202 (-2.6A)
 1.45A 6av6A-4nobA:
undetectable
6av6B-4nobA:
undetectable		 6av6A-4nobA:
20.49
6av6B-4nobA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4nob POLYMERIC
IMMUNOGLOBULIN
RECEPTOR
(Mus
musculus) 		4 / 6 ILE A  95
LEU A  84
ARG A  57
THR A  65
 None
None
EDO  A 204 (-4.0A)
None
 0.73A 6nmfN-4nobA:
undetectable
6nmfW-4nobA:
undetectable		 6nmfN-4nobA:
12.43
6nmfW-4nobA:
19.49