SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4noc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_A_BEZA11_0 (CES1 PROTEIN)	4noc	PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS (Kribbella flavida)	4 / 4	LEU A 91 SER A 17 LEU A 26 LEU A 47	None	1.13A	1yajA-4nocA: undetectable	1yajA-4nocA: 15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V3K_A_SAMA1254_0 (ESSENTIAL FOR MITOTIC GROWTH 1)	4noc	PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS (Kribbella flavida)	6 / 10	LEU A 47 VAL A 88 GLY A 33 LEU A 26 LEU A 25 ALA A 22	None	1.36A	2v3kA-4nocA: undetectable	2v3kA-4nocA: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VUF_B_FUAB2002_1 (SERUM ALBUMIN)	4noc	PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS (Kribbella flavida)	4 / 9	ILE A 114 ALA A 124 VAL A 123 CYH A 120	None	0.96A	2vufB-4nocA: undetectable	2vufB-4nocA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CJK_C_ACTC301_0 (IMMUNOGLOBULIN FAB LIGHT CHAIN)	4noc	PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS (Kribbella flavida)	4 / 4	VAL A 88 GLY A 14 ASP A 16 ASP A 38	None	1.45A	6cjkC-4nocA: undetectable	6cjkC-4nocA: 21.56

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YAJ_A_BEZA11_0","CES1 PROTEIN","4noc","PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS","Kribbella flavida",4,"LEU A  91;SER A  17;LEU A  26;LEU A  47","None","1.13A","1yajA-4nocA:undetectable","1yajA-4nocA:15.60"],["2V3K_A_SAMA1254_0","ESSENTIAL FOR MITOTIC GROWTH 1","4noc","PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS","Kribbella flavida",6,"LEU A  47;VAL A  88;GLY A  33;LEU A  26;LEU A  25;ALA A  22","None","1.36A","2v3kA-4nocA:undetectable","2v3kA-4nocA:22.27"],["2VUF_B_FUAB2002_1","SERUM ALBUMIN","4noc","PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS","Kribbella flavida",4,"ILE A 114;ALA A 124;VAL A 123;CYH A 120","None","0.96A","2vufB-4nocA:undetectable","2vufB-4nocA:14.73"],["6CJK_C_ACTC301_0","IMMUNOGLOBULIN FAB LIGHT CHAIN","4noc","PUTATIVE SIGNAL TRANSDUCTION PROTEIN WITH CBS DOMAINS","Kribbella flavida",4,"VAL A  88;GLY A  14;ASP A  16;ASP A  38","None","1.45A","6cjkC-4nocA:undetectable","6cjkC-4nocA:21.56"]]