SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4noh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_A_ID2A1_0
(THYMIDINE KINASE)		 4noh LIPOPROTEIN,
PUTATIVE
(Bacillus
anthracis) 		5 / 12 ILE A 164
TYR A  36
MET A  74
ALA A 147
TYR A 146
 None
 1.23A 1ki7A-4nohA:
undetectable		 1ki7A-4nohA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_D_TC9D1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4noh LIPOPROTEIN,
PUTATIVE
(Bacillus
anthracis) 		4 / 7 TYR A 146
TYR A  36
GLU A 188
TYR A 142
 None
 1.40A 2xytD-4nohA:
undetectable		 2xytD-4nohA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_G_TC9G1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4noh LIPOPROTEIN,
PUTATIVE
(Bacillus
anthracis) 		4 / 7 TYR A 146
TYR A  36
GLU A 188
TYR A 142
 None
 1.38A 2xytG-4nohA:
undetectable		 2xytG-4nohA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4noh LIPOPROTEIN,
PUTATIVE
(Bacillus
anthracis) 		4 / 7 TYR A 146
TYR A  36
GLU A 188
TYR A 142
 None
 1.38A 2xytH-4nohA:
undetectable		 2xytH-4nohA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 4noh LIPOPROTEIN,
PUTATIVE
(Bacillus
anthracis) 		5 / 12 LEU A  88
VAL A 134
GLY A 137
TYR A  36
HIS A 191
 None
 1.41A 3hgiA-4nohA:
undetectable		 3hgiA-4nohA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 4noh LIPOPROTEIN,
PUTATIVE
(Bacillus
anthracis) 		4 / 7 VAL A  71
ILE A  73
VAL A 112
ALA A 147
 None
 0.62A 5osrA-4nohA:
undetectable		 5osrA-4nohA:
20.12