SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4noo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4noo VGRG PROTEIN
(Vibrio
cholerae) 		4 / 7 LEU A 949
LEU A 954
LEU A 935
GLN A 914
 None
 1.02A 1kt3A-4nooA:
undetectable		 1kt3A-4nooA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 4noo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		5 / 12 SER B  59
ILE B  62
ASP B  63
ASN B  56
ILE B  57
 None
 1.25A 3ddyA-4nooB:
undetectable		 3ddyA-4nooB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4noo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		4 / 8 ASN B  98
LEU B 105
ALA B  47
ARG B  75
 None
 0.96A 3kp6A-4nooB:
2.3		 3kp6A-4nooB:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 4noo VGRG PROTEIN
(Vibrio
cholerae) 		4 / 5 ILE A 950
GLN A 914
ILE A 915
GLU A 926
 None
 1.16A 4a99D-4nooA:
undetectable		 4a99D-4nooA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4noo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Vibrio
cholerae) 		5 / 12 ASN B  98
LEU B 105
ALA B  47
TYR B  71
ARG B  75
 None
 1.09A 4ejwA-4nooB:
2.2		 4ejwA-4nooB:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 4noo VGRG PROTEIN
(Vibrio
cholerae) 		3 / 3 TYR A 826
GLN A 972
TRP A 937
 None
 0.95A 4kn2C-4nooA:
undetectable		 4kn2C-4nooA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4noo VGRG PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 922
MET A 959
GLN A 914
ILE A 950
PHE A 925
 None
 1.17A 4zvmA-4nooA:
undetectable
4zvmB-4nooA:
undetectable		 4zvmA-4nooA:
20.17
4zvmB-4nooA:
20.17