SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4noz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4noz ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Burkholderia
cenocepacia) 		5 / 9 LEU A 101
LEU A 138
ILE A 117
PHE A  61
ILE A  82
 None
 1.07A 2f78A-4nozA:
undetectable		 2f78A-4nozA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4noz ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Burkholderia
cenocepacia) 		5 / 9 LEU A 101
LEU A 138
ILE A 117
PHE A  61
ILE A  82
 None
 1.11A 2f78B-4nozA:
undetectable		 2f78B-4nozA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4noz ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Burkholderia
cenocepacia) 		5 / 9 LEU A 101
LEU A 138
ILE A 117
PHE A  61
ILE A  82
 None
 1.15A 2f7aA-4nozA:
undetectable		 2f7aA-4nozA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 4noz ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Burkholderia
cenocepacia) 		5 / 12 LEU A 108
GLY A 107
LEU A 105
ILE A  76
ALA A  81
 None
 1.06A 3gwwA-4nozA:
undetectable		 3gwwA-4nozA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4noz ORGANIC
HYDROPEROXIDE
RESISTANCE PROTEIN
(Burkholderia
cenocepacia) 		3 / 3 HIS A  11
SER A  27
GLU A  26
 None
 0.83A 3s8pA-4nozA:
undetectable		 3s8pA-4nozA:
20.51