SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nps'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
clarridgeiae) 		3 / 3 HIS A 168
ARG A  92
GLU A 172
 None
 1.19A 3qf1A-4npsA:
undetectable		 3qf1A-4npsA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
clarridgeiae) 		3 / 3 TYR A 166
LEU A  76
LYS A  74
 None
 0.77A 3sueD-4npsA:
undetectable		 3sueD-4npsA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
clarridgeiae) 		3 / 3 THR A 209
ASN A 215
SER A 214
 None
 0.68A 4tvtA-4npsA:
undetectable		 4tvtA-4npsA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
clarridgeiae) 		3 / 3 TYR A 264
THR A 307
THR A 280
 None
 0.80A 5aoxB-4npsA:
undetectable		 5aoxB-4npsA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
clarridgeiae) 		3 / 3 TYR A 264
THR A 307
THR A 280
 None
 0.83A 5aoxE-4npsA:
undetectable		 5aoxE-4npsA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
clarridgeiae) 		3 / 3 LYS A 279
ASP A 281
ILE A 276
 None
 0.81A 5kc4E-4npsA:
1.8		 5kc4E-4npsA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)		 4nps BARTONELLA EFFECTOR
PROTEIN (BEP)
SUBSTRATE OF VIRB
T4SS
(Bartonella
clarridgeiae) 		3 / 3 SER A 272
SER A 275
ALA A 233
 None
 0.72A 6dwnC-4npsA:
undetectable		 6dwnC-4npsA:
8.66