SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 1c9sA-4nq1A:
undetectable
1c9sK-4nq1A:
undetectable		 1c9sA-4nq1A:
15.71
1c9sK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 GLY A  75
ALA A  96
THR A  88
THR A  76
ILE A  59
 None
 1.22A 1c9sA-4nq1A:
undetectable
1c9sB-4nq1A:
undetectable		 1c9sA-4nq1A:
15.71
1c9sB-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 1c9sB-4nq1A:
undetectable
1c9sC-4nq1A:
undetectable		 1c9sB-4nq1A:
15.71
1c9sC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1c9sC-4nq1A:
undetectable
1c9sD-4nq1A:
undetectable		 1c9sC-4nq1A:
15.71
1c9sD-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 GLY A  75
ALA A  96
THR A  88
THR A  76
ILE A  59
 None
 1.21A 1c9sD-4nq1A:
undetectable
1c9sE-4nq1A:
undetectable		 1c9sD-4nq1A:
15.71
1c9sE-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 1c9sD-4nq1A:
undetectable
1c9sE-4nq1A:
undetectable		 1c9sD-4nq1A:
15.71
1c9sE-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.49A 1c9sD-4nq1A:
undetectable
1c9sE-4nq1A:
undetectable		 1c9sD-4nq1A:
15.71
1c9sE-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1c9sE-4nq1A:
undetectable
1c9sF-4nq1A:
undetectable		 1c9sE-4nq1A:
15.71
1c9sF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 1c9sF-4nq1A:
undetectable
1c9sG-4nq1A:
undetectable		 1c9sF-4nq1A:
15.71
1c9sG-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1c9sG-4nq1A:
undetectable
1c9sH-4nq1A:
undetectable		 1c9sG-4nq1A:
15.71
1c9sH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 1c9sH-4nq1A:
undetectable
1c9sI-4nq1A:
undetectable		 1c9sH-4nq1A:
15.71
1c9sI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 1c9sJ-4nq1A:
undetectable
1c9sK-4nq1A:
undetectable		 1c9sJ-4nq1A:
15.71
1c9sK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 1c9sO-4nq1A:
undetectable
1c9sP-4nq1A:
undetectable		 1c9sO-4nq1A:
15.71
1c9sP-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.50A 1gtfA-4nq1A:
undetectable
1gtfK-4nq1A:
undetectable		 1gtfA-4nq1A:
15.71
1gtfK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 1gtfA-4nq1A:
undetectable
1gtfK-4nq1A:
undetectable		 1gtfA-4nq1A:
15.71
1gtfK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.41A 1gtfB-4nq1A:
undetectable
1gtfC-4nq1A:
undetectable		 1gtfB-4nq1A:
15.71
1gtfC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1gtfC-4nq1A:
undetectable
1gtfD-4nq1A:
undetectable		 1gtfC-4nq1A:
15.71
1gtfD-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1gtfE-4nq1A:
undetectable
1gtfF-4nq1A:
undetectable		 1gtfE-4nq1A:
15.71
1gtfF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.50A 1gtfE-4nq1A:
undetectable
1gtfF-4nq1A:
undetectable		 1gtfE-4nq1A:
15.71
1gtfF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1gtfG-4nq1A:
undetectable
1gtfH-4nq1A:
undetectable		 1gtfG-4nq1A:
15.71
1gtfH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1gtfH-4nq1A:
undetectable
1gtfI-4nq1A:
undetectable		 1gtfH-4nq1A:
15.71
1gtfI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 1gtfI-4nq1A:
undetectable
1gtfJ-4nq1A:
undetectable		 1gtfI-4nq1A:
15.71
1gtfJ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.49A 1gtfI-4nq1A:
undetectable
1gtfJ-4nq1A:
undetectable		 1gtfI-4nq1A:
15.71
1gtfJ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 1gtfP-4nq1A:
undetectable
1gtfQ-4nq1A:
undetectable		 1gtfP-4nq1A:
15.71
1gtfQ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 1gtfT-4nq1A:
undetectable
1gtfU-4nq1A:
undetectable		 1gtfT-4nq1A:
15.71
1gtfU-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.41A 1gtfL-4nq1A:
undetectable
1gtfV-4nq1A:
undetectable		 1gtfL-4nq1A:
15.71
1gtfV-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1gtnG-4nq1A:
undetectable
1gtnH-4nq1A:
undetectable		 1gtnG-4nq1A:
15.71
1gtnH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 MET A 213
LEU A 219
ALA A 220
LEU A 195
HIS A 239
 None
 1.35A 1gwrB-4nq1A:
undetectable		 1gwrB-4nq1A:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 7 LEU A 235
ASP A 187
LEU A 242
MET A 213
 None
 0.94A 1n13I-4nq1A:
undetectable
1n13L-4nq1A:
undetectable		 1n13I-4nq1A:
11.38
1n13L-4nq1A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		3 / 3 GLU A  25
HIS A  22
HIS A  21
 None
 0.64A 1oe2A-4nq1A:
undetectable		 1oe2A-4nq1A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 GLY A  75
ALA A  96
THR A  88
THR A  76
ILE A  59
 None
 1.21A 1utdA-4nq1A:
undetectable
1utdB-4nq1A:
undetectable		 1utdA-4nq1A:
15.71
1utdB-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 1utdA-4nq1A:
undetectable
1utdB-4nq1A:
undetectable		 1utdA-4nq1A:
15.71
1utdB-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 GLY A  75
ALA A  96
THR A  88
THR A  76
ILE A  59
 None
 1.20A 1utdC-4nq1A:
undetectable
1utdD-4nq1A:
undetectable		 1utdC-4nq1A:
15.71
1utdD-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.38A 1utdC-4nq1A:
undetectable
1utdD-4nq1A:
undetectable		 1utdC-4nq1A:
15.71
1utdD-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 1utdD-4nq1A:
undetectable
1utdE-4nq1A:
undetectable		 1utdD-4nq1A:
15.71
1utdE-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.49A 1utdG-4nq1A:
undetectable
1utdH-4nq1A:
undetectable		 1utdG-4nq1A:
15.71
1utdH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.37A 1utdG-4nq1A:
undetectable
1utdH-4nq1A:
undetectable		 1utdG-4nq1A:
15.71
1utdH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.39A 1utdA-4nq1A:
undetectable
1utdK-4nq1A:
undetectable		 1utdA-4nq1A:
15.71
1utdK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 1utdN-4nq1A:
undetectable
1utdO-4nq1A:
undetectable		 1utdN-4nq1A:
15.71
1utdO-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 1utdR-4nq1A:
undetectable
1utdS-4nq1A:
undetectable		 1utdR-4nq1A:
15.71
1utdS-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 6 LEU A 212
MET A 258
MET A 255
LEU A 284
 None
 1.38A 2oz7A-4nq1A:
undetectable		 2oz7A-4nq1A:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 7 MET A 213
LEU A 235
ASP A 187
LEU A 242
 None
 0.98A 2qqcB-4nq1A:
undetectable
2qqcC-4nq1A:
undetectable		 2qqcB-4nq1A:
20.00
2qqcC-4nq1A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 7 LEU A 235
ASP A 187
LEU A 242
MET A 213
 None
 0.98A 2qqcA-4nq1A:
undetectable
2qqcF-4nq1A:
undetectable		 2qqcA-4nq1A:
12.59
2qqcF-4nq1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 7 LEU A 235
ASP A 187
LEU A 242
MET A 213
 None
 0.98A 2qqcG-4nq1A:
undetectable
2qqcJ-4nq1A:
undetectable		 2qqcG-4nq1A:
12.59
2qqcJ-4nq1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 7 LEU A 235
ASP A 187
LEU A 242
MET A 213
 None
 0.95A 2qqcI-4nq1A:
undetectable
2qqcL-4nq1A:
undetectable		 2qqcI-4nq1A:
12.59
2qqcL-4nq1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 7 LEU A 235
ASP A 187
LEU A 242
MET A 213
 None
 0.97A 2qqdA-4nq1A:
undetectable
2qqdE-4nq1A:
undetectable		 2qqdA-4nq1A:
13.72
2qqdE-4nq1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 7 TYR A  94
ALA A  74
ALA A  41
THR A  11
 None
 0.90A 2wx2A-4nq1A:
undetectable		 2wx2A-4nq1A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 8 ALA A  74
ALA A  41
THR A  11
LEU A  23
 None
 0.91A 2wx2B-4nq1A:
undetectable		 2wx2B-4nq1A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_B_2FAB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.28A 2zj0B-4nq1A:
undetectable		 2zj0B-4nq1A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.27A 3ce6A-4nq1A:
undetectable		 3ce6A-4nq1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.25A 3ce6B-4nq1A:
undetectable		 3ce6B-4nq1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.25A 3ce6C-4nq1A:
undetectable		 3ce6C-4nq1A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_A_ADNA438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 4 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.26A 3g1uA-4nq1A:
undetectable		 3g1uA-4nq1A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.27A 3g1uC-4nq1A:
undetectable		 3g1uC-4nq1A:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 6 LEU A 143
MET A 142
ILE A  85
ILE A 101
 None
 0.75A 3gcsA-4nq1A:
undetectable		 3gcsA-4nq1A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.27A 3glqA-4nq1A:
undetectable		 3glqA-4nq1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.25A 3glqB-4nq1A:
undetectable		 3glqB-4nq1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 8 ALA A  74
ALA A  41
THR A  11
LEU A  23
 None
 0.97A 3khmA-4nq1A:
undetectable		 3khmA-4nq1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KHM_A_TPFA501_1
(STEROL 14
ALPHA-DEMETHYLASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 8 TYR A  94
ALA A  74
ALA A  41
THR A  11
 None
 0.93A 3khmA-4nq1A:
undetectable		 3khmA-4nq1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.28A 3n58A-4nq1A:
2.0		 3n58A-4nq1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		3 / 3 ALA A 126
VAL A 125
GLN A  89
 None
 0.67A 3of4B-4nq1A:
undetectable		 3of4B-4nq1A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		3 / 3 GLY A 185
SER A 184
TRP A 193
 KPI  A 160 ( 3.8A)
None
None
 0.97A 4e7cD-4nq1A:
undetectable		 4e7cD-4nq1A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 11 ALA A  74
ALA A  40
ALA A  41
THR A  11
VAL A  18
 None
 1.12A 4j6cA-4nq1A:
undetectable		 4j6cA-4nq1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 ALA A  74
ALA A  40
ALA A  41
THR A  11
VAL A  18
 None
 1.14A 4j6cB-4nq1A:
undetectable		 4j6cB-4nq1A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		3 / 3 ARG A 174
LEU A 175
GLU A 177
 None
 0.67A 4l3gF-4nq1A:
undetectable		 4l3gF-4nq1A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.29A 4lvcA-4nq1A:
undetectable		 4lvcA-4nq1A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.29A 4lvcC-4nq1A:
undetectable		 4lvcC-4nq1A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 MET A 213
LEU A 219
ALA A 220
LEU A 195
HIS A 239
 None
 1.35A 5dx3A-4nq1A:
undetectable		 5dx3A-4nq1A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 4 VAL A 125
ALA A  91
ILE A 101
THR A  76
 None
 0.99A 5e4dB-4nq1A:
undetectable		 5e4dB-4nq1A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.43A 5eeuA-4nq1A:
undetectable
5eeuB-4nq1A:
undetectable		 5eeuA-4nq1A:
15.71
5eeuB-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5eeuB-4nq1A:
undetectable
5eeuC-4nq1A:
undetectable		 5eeuB-4nq1A:
15.71
5eeuC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5eeuB-4nq1A:
undetectable
5eeuC-4nq1A:
undetectable		 5eeuB-4nq1A:
15.71
5eeuC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.41A 5eeuE-4nq1A:
undetectable
5eeuF-4nq1A:
undetectable		 5eeuE-4nq1A:
15.71
5eeuF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eeuG-4nq1A:
undetectable
5eeuH-4nq1A:
undetectable		 5eeuG-4nq1A:
15.71
5eeuH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eeuH-4nq1A:
undetectable
5eeuI-4nq1A:
undetectable		 5eeuH-4nq1A:
15.71
5eeuI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5eeuJ-4nq1A:
undetectable
5eeuK-4nq1A:
undetectable		 5eeuJ-4nq1A:
15.71
5eeuK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.50A 5eeuA-4nq1A:
undetectable
5eeuK-4nq1A:
undetectable		 5eeuA-4nq1A:
15.71
5eeuK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5eeuA-4nq1A:
undetectable
5eeuK-4nq1A:
undetectable		 5eeuA-4nq1A:
15.71
5eeuK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eeuN-4nq1A:
undetectable
5eeuO-4nq1A:
undetectable		 5eeuN-4nq1A:
15.71
5eeuO-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5eeuP-4nq1A:
undetectable
5eeuQ-4nq1A:
undetectable		 5eeuP-4nq1A:
15.71
5eeuQ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5eeuR-4nq1A:
undetectable
5eeuS-4nq1A:
undetectable		 5eeuR-4nq1A:
15.71
5eeuS-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5eeuS-4nq1A:
undetectable
5eeuT-4nq1A:
undetectable		 5eeuS-4nq1A:
15.71
5eeuT-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eeuT-4nq1A:
undetectable
5eeuU-4nq1A:
undetectable		 5eeuT-4nq1A:
15.71
5eeuU-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5eeuU-4nq1A:
undetectable
5eeuV-4nq1A:
undetectable		 5eeuU-4nq1A:
15.71
5eeuV-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5eevB-4nq1A:
undetectable
5eevC-4nq1A:
undetectable		 5eevB-4nq1A:
15.71
5eevC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5eevB-4nq1A:
undetectable
5eevC-4nq1A:
undetectable		 5eevB-4nq1A:
15.71
5eevC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.41A 5eevE-4nq1A:
undetectable
5eevF-4nq1A:
undetectable		 5eevE-4nq1A:
15.71
5eevF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eevG-4nq1A:
undetectable
5eevH-4nq1A:
undetectable		 5eevG-4nq1A:
15.71
5eevH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eevH-4nq1A:
undetectable
5eevI-4nq1A:
undetectable		 5eevH-4nq1A:
15.71
5eevI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.50A 5eevH-4nq1A:
undetectable
5eevI-4nq1A:
undetectable		 5eevH-4nq1A:
15.71
5eevI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.50A 5eevA-4nq1A:
undetectable
5eevK-4nq1A:
undetectable		 5eevA-4nq1A:
15.71
5eevK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5eevA-4nq1A:
undetectable
5eevK-4nq1A:
undetectable		 5eevA-4nq1A:
15.71
5eevK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eevN-4nq1A:
undetectable
5eevO-4nq1A:
undetectable		 5eevN-4nq1A:
15.71
5eevO-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eevP-4nq1A:
undetectable
5eevQ-4nq1A:
undetectable		 5eevP-4nq1A:
15.71
5eevQ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5eevR-4nq1A:
undetectable
5eevS-4nq1A:
undetectable		 5eevR-4nq1A:
15.71
5eevS-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5eevS-4nq1A:
undetectable
5eevT-4nq1A:
undetectable		 5eevS-4nq1A:
15.71
5eevT-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eevT-4nq1A:
undetectable
5eevU-4nq1A:
undetectable		 5eevT-4nq1A:
15.71
5eevU-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5eewB-4nq1A:
undetectable
5eewC-4nq1A:
undetectable		 5eewB-4nq1A:
15.71
5eewC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5eewB-4nq1A:
undetectable
5eewC-4nq1A:
undetectable		 5eewB-4nq1A:
15.71
5eewC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.41A 5eewE-4nq1A:
undetectable
5eewF-4nq1A:
undetectable		 5eewE-4nq1A:
15.71
5eewF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eewG-4nq1A:
undetectable
5eewH-4nq1A:
undetectable		 5eewG-4nq1A:
15.71
5eewH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eewH-4nq1A:
undetectable
5eewI-4nq1A:
undetectable		 5eewH-4nq1A:
15.71
5eewI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.49A 5eewA-4nq1A:
undetectable
5eewK-4nq1A:
undetectable		 5eewA-4nq1A:
15.71
5eewK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5eewA-4nq1A:
undetectable
5eewK-4nq1A:
undetectable		 5eewA-4nq1A:
15.71
5eewK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eewN-4nq1A:
undetectable
5eewO-4nq1A:
undetectable		 5eewN-4nq1A:
15.71
5eewO-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eewP-4nq1A:
undetectable
5eewQ-4nq1A:
undetectable		 5eewP-4nq1A:
15.71
5eewQ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5eewR-4nq1A:
undetectable
5eewS-4nq1A:
undetectable		 5eewR-4nq1A:
15.71
5eewS-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eewS-4nq1A:
undetectable
5eewT-4nq1A:
undetectable		 5eewS-4nq1A:
15.71
5eewT-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eewT-4nq1A:
undetectable
5eewU-4nq1A:
undetectable		 5eewT-4nq1A:
15.71
5eewU-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5eexB-4nq1A:
undetectable
5eexC-4nq1A:
undetectable		 5eexB-4nq1A:
15.71
5eexC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5eexB-4nq1A:
undetectable
5eexC-4nq1A:
undetectable		 5eexB-4nq1A:
15.71
5eexC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.41A 5eexE-4nq1A:
undetectable
5eexF-4nq1A:
undetectable		 5eexE-4nq1A:
15.71
5eexF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eexG-4nq1A:
undetectable
5eexH-4nq1A:
undetectable		 5eexG-4nq1A:
15.71
5eexH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eexH-4nq1A:
undetectable
5eexI-4nq1A:
undetectable		 5eexH-4nq1A:
15.71
5eexI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5eexA-4nq1A:
undetectable
5eexK-4nq1A:
undetectable		 5eexA-4nq1A:
15.71
5eexK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eexN-4nq1A:
undetectable
5eexO-4nq1A:
undetectable		 5eexN-4nq1A:
15.71
5eexO-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5eexP-4nq1A:
undetectable
5eexQ-4nq1A:
undetectable		 5eexP-4nq1A:
15.71
5eexQ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5eexQ-4nq1A:
undetectable
5eexR-4nq1A:
undetectable		 5eexQ-4nq1A:
15.71
5eexR-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5eexR-4nq1A:
undetectable
5eexS-4nq1A:
undetectable		 5eexR-4nq1A:
15.71
5eexS-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5eexS-4nq1A:
undetectable
5eexT-4nq1A:
undetectable		 5eexS-4nq1A:
15.71
5eexT-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eexT-4nq1A:
undetectable
5eexU-4nq1A:
undetectable		 5eexT-4nq1A:
15.71
5eexU-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5eeyB-4nq1A:
undetectable
5eeyC-4nq1A:
undetectable		 5eeyB-4nq1A:
15.71
5eeyC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5eeyB-4nq1A:
undetectable
5eeyC-4nq1A:
undetectable		 5eeyB-4nq1A:
15.71
5eeyC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.41A 5eeyE-4nq1A:
undetectable
5eeyF-4nq1A:
undetectable		 5eeyE-4nq1A:
15.71
5eeyF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eeyG-4nq1A:
undetectable
5eeyH-4nq1A:
undetectable		 5eeyG-4nq1A:
15.71
5eeyH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eeyH-4nq1A:
undetectable
5eeyI-4nq1A:
undetectable		 5eeyH-4nq1A:
15.71
5eeyI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.49A 5eeyH-4nq1A:
undetectable
5eeyI-4nq1A:
undetectable		 5eeyH-4nq1A:
15.71
5eeyI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.50A 5eeyA-4nq1A:
undetectable
5eeyK-4nq1A:
undetectable		 5eeyA-4nq1A:
15.71
5eeyK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5eeyA-4nq1A:
undetectable
5eeyK-4nq1A:
undetectable		 5eeyA-4nq1A:
15.71
5eeyK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eeyN-4nq1A:
undetectable
5eeyO-4nq1A:
undetectable		 5eeyN-4nq1A:
15.71
5eeyO-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eeyP-4nq1A:
undetectable
5eeyQ-4nq1A:
undetectable		 5eeyP-4nq1A:
15.71
5eeyQ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5eeyQ-4nq1A:
undetectable
5eeyR-4nq1A:
undetectable		 5eeyQ-4nq1A:
15.71
5eeyR-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5eeyR-4nq1A:
undetectable
5eeyS-4nq1A:
undetectable		 5eeyR-4nq1A:
15.71
5eeyS-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eeyT-4nq1A:
undetectable
5eeyU-4nq1A:
undetectable		 5eeyT-4nq1A:
15.71
5eeyU-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5eezB-4nq1A:
undetectable
5eezC-4nq1A:
undetectable		 5eezB-4nq1A:
15.71
5eezC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5eezB-4nq1A:
undetectable
5eezC-4nq1A:
undetectable		 5eezB-4nq1A:
15.71
5eezC-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5eezE-4nq1A:
undetectable
5eezF-4nq1A:
undetectable		 5eezE-4nq1A:
15.71
5eezF-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eezG-4nq1A:
undetectable
5eezH-4nq1A:
undetectable		 5eezG-4nq1A:
15.71
5eezH-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5eezH-4nq1A:
undetectable
5eezI-4nq1A:
undetectable		 5eezH-4nq1A:
15.71
5eezI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.50A 5eezH-4nq1A:
undetectable
5eezI-4nq1A:
undetectable		 5eezH-4nq1A:
15.71
5eezI-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5eezJ-4nq1A:
undetectable
5eezK-4nq1A:
undetectable		 5eezJ-4nq1A:
15.71
5eezK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.50A 5eezA-4nq1A:
undetectable
5eezK-4nq1A:
undetectable		 5eezA-4nq1A:
15.71
5eezK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5eezA-4nq1A:
undetectable
5eezK-4nq1A:
undetectable		 5eezA-4nq1A:
15.71
5eezK-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eezN-4nq1A:
undetectable
5eezO-4nq1A:
undetectable		 5eezN-4nq1A:
15.71
5eezO-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5eezP-4nq1A:
undetectable
5eezQ-4nq1A:
undetectable		 5eezP-4nq1A:
15.71
5eezQ-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5eezQ-4nq1A:
undetectable
5eezR-4nq1A:
undetectable		 5eezQ-4nq1A:
15.71
5eezR-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5eezR-4nq1A:
undetectable
5eezS-4nq1A:
undetectable		 5eezR-4nq1A:
15.71
5eezS-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5eezT-4nq1A:
undetectable
5eezU-4nq1A:
undetectable		 5eezT-4nq1A:
15.71
5eezU-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5ef0B-4nq1A:
undetectable
5ef0C-4nq1A:
undetectable		 5ef0B-4nq1A:
15.71
5ef0C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5ef0B-4nq1A:
undetectable
5ef0C-4nq1A:
undetectable		 5ef0B-4nq1A:
15.71
5ef0C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef0E-4nq1A:
undetectable
5ef0F-4nq1A:
undetectable		 5ef0E-4nq1A:
15.71
5ef0F-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef0G-4nq1A:
undetectable
5ef0H-4nq1A:
undetectable		 5ef0G-4nq1A:
15.71
5ef0H-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef0H-4nq1A:
undetectable
5ef0I-4nq1A:
undetectable		 5ef0H-4nq1A:
15.71
5ef0I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.49A 5ef0H-4nq1A:
undetectable
5ef0I-4nq1A:
undetectable		 5ef0H-4nq1A:
15.71
5ef0I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef0J-4nq1A:
undetectable
5ef0K-4nq1A:
undetectable		 5ef0J-4nq1A:
15.71
5ef0K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5ef0A-4nq1A:
undetectable
5ef0K-4nq1A:
undetectable		 5ef0A-4nq1A:
15.71
5ef0K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5ef0N-4nq1A:
undetectable
5ef0O-4nq1A:
undetectable		 5ef0N-4nq1A:
15.71
5ef0O-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5ef0P-4nq1A:
undetectable
5ef0Q-4nq1A:
undetectable		 5ef0P-4nq1A:
15.71
5ef0Q-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5ef0Q-4nq1A:
undetectable
5ef0R-4nq1A:
undetectable		 5ef0Q-4nq1A:
15.71
5ef0R-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5ef0R-4nq1A:
undetectable
5ef0S-4nq1A:
undetectable		 5ef0R-4nq1A:
15.71
5ef0S-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef0T-4nq1A:
undetectable
5ef0U-4nq1A:
undetectable		 5ef0T-4nq1A:
15.71
5ef0U-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5ef1B-4nq1A:
undetectable
5ef1C-4nq1A:
undetectable		 5ef1B-4nq1A:
15.71
5ef1C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5ef1B-4nq1A:
undetectable
5ef1C-4nq1A:
undetectable		 5ef1B-4nq1A:
15.71
5ef1C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef1E-4nq1A:
undetectable
5ef1F-4nq1A:
undetectable		 5ef1E-4nq1A:
15.71
5ef1F-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef1G-4nq1A:
undetectable
5ef1H-4nq1A:
undetectable		 5ef1G-4nq1A:
15.71
5ef1H-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef1H-4nq1A:
undetectable
5ef1I-4nq1A:
undetectable		 5ef1H-4nq1A:
15.71
5ef1I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.49A 5ef1H-4nq1A:
undetectable
5ef1I-4nq1A:
undetectable		 5ef1H-4nq1A:
15.71
5ef1I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef1J-4nq1A:
undetectable
5ef1K-4nq1A:
undetectable		 5ef1J-4nq1A:
15.71
5ef1K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.49A 5ef1A-4nq1A:
undetectable
5ef1K-4nq1A:
undetectable		 5ef1A-4nq1A:
15.71
5ef1K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5ef1A-4nq1A:
undetectable
5ef1K-4nq1A:
undetectable		 5ef1A-4nq1A:
15.71
5ef1K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef1N-4nq1A:
undetectable
5ef1O-4nq1A:
undetectable		 5ef1N-4nq1A:
15.71
5ef1O-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5ef1P-4nq1A:
undetectable
5ef1Q-4nq1A:
undetectable		 5ef1P-4nq1A:
15.71
5ef1Q-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5ef1Q-4nq1A:
undetectable
5ef1R-4nq1A:
undetectable		 5ef1Q-4nq1A:
15.71
5ef1R-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5ef1R-4nq1A:
undetectable
5ef1S-4nq1A:
undetectable		 5ef1R-4nq1A:
15.71
5ef1S-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef1T-4nq1A:
undetectable
5ef1U-4nq1A:
undetectable		 5ef1T-4nq1A:
15.71
5ef1U-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5ef2B-4nq1A:
undetectable
5ef2C-4nq1A:
undetectable		 5ef2B-4nq1A:
15.71
5ef2C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5ef2B-4nq1A:
undetectable
5ef2C-4nq1A:
undetectable		 5ef2B-4nq1A:
15.71
5ef2C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef2E-4nq1A:
undetectable
5ef2F-4nq1A:
undetectable		 5ef2E-4nq1A:
15.71
5ef2F-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef2G-4nq1A:
undetectable
5ef2H-4nq1A:
undetectable		 5ef2G-4nq1A:
15.71
5ef2H-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef2H-4nq1A:
undetectable
5ef2I-4nq1A:
undetectable		 5ef2H-4nq1A:
15.71
5ef2I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.49A 5ef2H-4nq1A:
undetectable
5ef2I-4nq1A:
undetectable		 5ef2H-4nq1A:
15.71
5ef2I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef2J-4nq1A:
undetectable
5ef2K-4nq1A:
undetectable		 5ef2J-4nq1A:
15.71
5ef2K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
ILE A 129
THR A  81
SER A 124
 None
None
None
MRD  A 301 ( 4.2A)
None
 1.49A 5ef2A-4nq1A:
undetectable
5ef2K-4nq1A:
undetectable		 5ef2A-4nq1A:
15.71
5ef2K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5ef2A-4nq1A:
undetectable
5ef2K-4nq1A:
undetectable		 5ef2A-4nq1A:
15.71
5ef2K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef2N-4nq1A:
undetectable
5ef2O-4nq1A:
undetectable		 5ef2N-4nq1A:
15.71
5ef2O-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5ef2P-4nq1A:
undetectable
5ef2Q-4nq1A:
undetectable		 5ef2P-4nq1A:
15.71
5ef2Q-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.43A 5ef2Q-4nq1A:
undetectable
5ef2R-4nq1A:
undetectable		 5ef2Q-4nq1A:
15.71
5ef2R-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5ef2R-4nq1A:
undetectable
5ef2S-4nq1A:
undetectable		 5ef2R-4nq1A:
15.71
5ef2S-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef2T-4nq1A:
undetectable
5ef2U-4nq1A:
undetectable		 5ef2T-4nq1A:
15.71
5ef2U-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.37A 5ef3B-4nq1A:
undetectable
5ef3C-4nq1A:
undetectable		 5ef3B-4nq1A:
15.71
5ef3C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.47A 5ef3B-4nq1A:
undetectable
5ef3C-4nq1A:
undetectable		 5ef3B-4nq1A:
15.71
5ef3C-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef3E-4nq1A:
undetectable
5ef3F-4nq1A:
undetectable		 5ef3E-4nq1A:
15.71
5ef3F-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef3G-4nq1A:
undetectable
5ef3H-4nq1A:
undetectable		 5ef3G-4nq1A:
15.71
5ef3H-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.38A 5ef3H-4nq1A:
undetectable
5ef3I-4nq1A:
undetectable		 5ef3H-4nq1A:
15.71
5ef3I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 THR A  81
SER A 124
HIS A 117
ALA A 122
ILE A 129
 MRD  A 301 ( 4.2A)
None
None
None
None
 1.49A 5ef3H-4nq1A:
undetectable
5ef3I-4nq1A:
undetectable		 5ef3H-4nq1A:
15.71
5ef3I-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 SER A 124
HIS A 117
ALA A 122
THR A  88
ILE A 129
 None
 1.40A 5ef3J-4nq1A:
undetectable
5ef3K-4nq1A:
undetectable		 5ef3J-4nq1A:
15.71
5ef3K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.39A 5ef3A-4nq1A:
undetectable
5ef3K-4nq1A:
undetectable		 5ef3A-4nq1A:
15.71
5ef3K-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef3N-4nq1A:
undetectable
5ef3O-4nq1A:
undetectable		 5ef3N-4nq1A:
15.71
5ef3O-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.41A 5ef3P-4nq1A:
undetectable
5ef3Q-4nq1A:
undetectable		 5ef3P-4nq1A:
15.71
5ef3Q-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 9 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef3Q-4nq1A:
undetectable
5ef3R-4nq1A:
undetectable		 5ef3Q-4nq1A:
15.71
5ef3R-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.40A 5ef3R-4nq1A:
undetectable
5ef3S-4nq1A:
undetectable		 5ef3R-4nq1A:
15.71
5ef3S-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 HIS A 117
ALA A 122
THR A  88
ILE A 129
SER A 124
 None
 1.42A 5ef3T-4nq1A:
undetectable
5ef3U-4nq1A:
undetectable		 5ef3T-4nq1A:
15.71
5ef3U-4nq1A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 12 ASP A 186
THR A  35
GLY A   4
SER A   3
SER A 184
 None
 1.22A 5hfjF-4nq1A:
undetectable		 5hfjF-4nq1A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 11 MET A 213
LEU A 219
ALA A 220
LEU A 195
HIS A 239
 None
 1.35A 5hyrB-4nq1A:
undetectable		 5hyrB-4nq1A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 12 LEU A  87
GLY A  42
LEU A  23
ILE A  59
LEU A 265
 None
KPI  A 160 ( 3.5A)
None
None
None
 1.19A 5y2tA-4nq1A:
undetectable		 5y2tA-4nq1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.27A 6aphA-4nq1A:
undetectable		 6aphA-4nq1A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		5 / 10 MET A 213
LEU A 219
ALA A 220
LEU A 195
HIS A 239
 None
 1.38A 6cbzB-4nq1A:
undetectable		 6cbzB-4nq1A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_A_ADNA505_2
(-)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 4 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.26A 6f3nA-4nq1A:
undetectable		 6f3nA-4nq1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_2
(-)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 4 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.27A 6f3nC-4nq1A:
undetectable		 6f3nC-4nq1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_D_ADND506_2
(-)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 4 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.27A 6f3nD-4nq1A:
undetectable		 6f3nD-4nq1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.28A 6gbnA-4nq1A:
2.0		 6gbnA-4nq1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.28A 6gbnB-4nq1A:
undetectable		 6gbnB-4nq1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 4nq1 4-HYDROXY-TETRAHYDRO
DIPICOLINATE
SYNTHASE
(Legionella
pneumophila) 		4 / 5 GLN A 111
THR A 110
THR A  81
HIS A 120
 None
None
MRD  A 301 ( 4.2A)
MRD  A 301 ( 4.8A)
 1.28A 6gbnD-4nq1A:
undetectable		 6gbnD-4nq1A:
21.43