SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nqe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E73_M_ASCM995_0
(MYROSINASE MA1)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 ILE A  96
ARG A   9
TYR A   7
PHE A 168
 2L4  A 301 (-4.0A)
2L4  A 301 (-3.5A)
2L4  A 301 (-3.7A)
None
 1.46A 1e73M-4nqeA:
undetectable		 1e73M-4nqeA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.82A 1usqA-4nqeA:
undetectable		 1usqA-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.83A 1usqB-4nqeA:
undetectable		 1usqB-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.80A 1usqC-4nqeA:
undetectable		 1usqC-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.84A 1usqD-4nqeA:
undetectable		 1usqD-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.84A 1usqE-4nqeA:
undetectable		 1usqE-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_A_CLMA1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.81A 2jkjA-4nqeA:
undetectable		 2jkjA-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_B_CLMB1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.82A 2jkjB-4nqeA:
undetectable		 2jkjB-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_C_CLMC1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.81A 2jkjC-4nqeA:
undetectable		 2jkjC-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.84A 2jklA-4nqeA:
undetectable		 2jklA-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_B_CLMB1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 6 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.83A 2jklB-4nqeA:
undetectable		 2jklB-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.83A 2jklC-4nqeA:
undetectable		 2jklC-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.85A 2jklD-4nqeA:
undetectable		 2jklD-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		4 / 7 PRO A 232
GLY A 234
GLY A 236
TYR A 238
 None
 0.84A 2jklF-4nqeA:
undetectable		 2jklF-4nqeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		3 / 3 TYR A  36
ARG A  41
SER A  38
 None
 1.18A 4dr2I-4nqeA:
undetectable
4dr2J-4nqeA:
undetectable		 4dr2I-4nqeA:
18.18
4dr2J-4nqeA:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 4nqe MAJOR
HISTOCOMPATIBILITY
COMPLEX CLASS
I-RELATED GENE
PROTEIN
(Homo
sapiens) 		3 / 3 GLU A 149
TYR A 112
GLU A  76
 None
 0.56A 4ryaA-4nqeA:
undetectable		 4ryaA-4nqeA:
20.05