SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nqf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		4 / 8 SER A 213
HIS A 163
ASN A 211
TYR A 212
 None
 0.80A 1dssR-4nqfA:
undetectable		 1dssR-4nqfA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I9G_A_SAMA301_1
(HYPOTHETICAL PROTEIN
RV2118C)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		3 / 3 GLU A 199
HIS A 217
ASP A 170
 None
 0.87A 1i9gA-4nqfA:
undetectable		 1i9gA-4nqfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		5 / 10 LEU A 284
SER A 226
LEU A 233
ARG A 277
ARG A 223
 None
 1.30A 2ceoB-4nqfA:
undetectable		 2ceoB-4nqfA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		4 / 8 SER A 213
HIS A 163
ASN A 211
TYR A 212
 None
 0.78A 3dmtC-4nqfA:
undetectable		 3dmtC-4nqfA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		4 / 8 PHE A 192
ALA A 178
ALA A 197
THR A 200
 None
 1.04A 3t3sE-4nqfA:
undetectable		 3t3sE-4nqfA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		4 / 8 PHE A 192
ALA A 178
ALA A 197
THR A 200
 None
 0.89A 3t3sF-4nqfA:
undetectable		 3t3sF-4nqfA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y1D_D_DVAD5_0
(CYCLIC HEXAPEPTIDE
CYC[NDPOPPKID]
INTEGRASE)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		3 / 3 GLU A 253
LYS A 257
ASN A 252
 None
 1.00A 4y1dA-4nqfA:
undetectable
4y1dD-4nqfA:
undetectable		 4y1dA-4nqfA:
18.71
4y1dD-4nqfA:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		3 / 3 GLU A 199
HIS A 217
ASP A 170
 None
 0.86A 5c0oG-4nqfA:
undetectable		 5c0oG-4nqfA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 4nqf NUCLEOTIDYLTRANSFERA
SE
(Agrobacterium
fabrum) 		3 / 3 ALA A 197
GLN A 275
THR A 278
 None
 0.74A 5n0oA-4nqfA:
undetectable		 5n0oA-4nqfA:
17.47