SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nqg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 4nqg MITROCOMIN
(Mitrocoma
cellularia) 		3 / 3 ASP A 163
PHE A 157
VAL A 132
 None
 0.52A 1kijB-4nqgA:
undetectable		 1kijB-4nqgA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 4nqg MITROCOMIN
(Mitrocoma
cellularia) 		4 / 7 LEU A  56
LYS A 126
VAL A 132
LEU A 120
 None
None
None
CZH  A 201 (-4.9A)
 1.00A 4b3qA-4nqgA:
undetectable		 4b3qA-4nqgA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUF_A_ACTA310_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 4nqg MITROCOMIN
(Mitrocoma
cellularia) 		3 / 3 GLN A  38
THR A  85
THR A  86
 None
 0.82A 4fufA-4nqgA:
undetectable		 4fufA-4nqgA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4nqg MITROCOMIN
(Mitrocoma
cellularia) 		4 / 5 LYS A  99
LEU A 102
GLU A 103
LEU A  11
 None
 1.33A 4k4yA-4nqgA:
undetectable		 4k4yA-4nqgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4nqg MITROCOMIN
(Mitrocoma
cellularia) 		4 / 4 LYS A  99
LEU A 102
GLU A 103
LEU A  11
 None
 1.32A 4k4yE-4nqgA:
undetectable		 4k4yE-4nqgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4nqg MITROCOMIN
(Mitrocoma
cellularia) 		4 / 5 LYS A  99
LEU A 102
GLU A 103
LEU A  11
 None
 1.35A 4k4yI-4nqgA:
undetectable		 4k4yI-4nqgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4nqg MITROCOMIN
(Mitrocoma
cellularia) 		5 / 12 LEU A  56
LYS A 126
VAL A 132
PHE A 121
LEU A 120
 None
None
None
None
CZH  A 201 (-4.9A)
 1.43A 5cymA-4nqgA:
undetectable		 5cymA-4nqgA:
16.42