SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 4nqi SH3
DOMAIN-CONTAINING
PROTEIN
(Dictyostelium
discoideum) 		5 / 12 GLY A  72
GLY A  66
GLY A  67
LEU A  58
LEU A  61
 None
 0.99A 1eizA-4nqiA:
undetectable		 1eizA-4nqiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 4nqi SH3
DOMAIN-CONTAINING
PROTEIN
(Dictyostelium
discoideum) 		5 / 12 GLY A  72
GLY A  66
GLY A  67
LEU A  58
LEU A  61
 None
 0.96A 1ej0A-4nqiA:
undetectable		 1ej0A-4nqiA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_D_FOLD201_0
(FOLATE ECF
TRANSPORTER)		 4nqi SH3
DOMAIN-CONTAINING
PROTEIN
(Dictyostelium
discoideum) 		5 / 11 ARG A 181
ASP A 174
PHE A 116
ASN A 119
THR A 115
 None
 1.49A 4z7fD-4nqiA:
2.5		 4z7fD-4nqiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 4nqi SH3
DOMAIN-CONTAINING
PROTEIN
(Dictyostelium
discoideum) 		3 / 3 ARG A  86
LYS A 196
GLU A 199
 None
 0.66A 5d0yA-4nqiA:
3.5		 5d0yA-4nqiA:
19.17