SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 4nqk PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Homo
sapiens) 		4 / 5 GLN A 111
TRP A 167
LEU A 175
TRP A 186
 None
 1.47A 1ulvA-4nqkA:
undetectable		 1ulvA-4nqkA:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZV_B_ECNB411_1
(FLAVOHEMOGLOBIN)		 4nqk PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Homo
sapiens) 		5 / 9 ILE A 123
ILE A 124
LEU A 155
LEU A 171
ALA A 174
 None
 1.07A 3ozvB-4nqkA:
2.3		 3ozvB-4nqkA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB302_1
(BIFUNCTIONAL PROTEIN
FOLD)		 4nqk PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58
(Homo
sapiens) 		5 / 12 LEU A  58
LEU A   9
PHE A  73
ILE A  89
THR A  19
 None
 1.06A 6debB-4nqkA:
undetectable		 6debB-4nqkA:
19.70