SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		4 / 7 GLY A 289
HIS A 341
THR A 319
ILE A 290
 None
None
None
EDO  A 502 ( 4.0A)
 0.98A 1gtnF-4nqlA:
undetectable
1gtnG-4nqlA:
undetectable		 1gtnF-4nqlA:
17.05
1gtnG-4nqlA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		3 / 3 HIS A 406
HIS A 404
HIS A 356
 ZN  A 501 (-3.2A)
ZN  A 501 (-3.4A)
ZN  A 501 (-3.4A)
 0.38A 2ozrF-4nqlA:
undetectable		 2ozrF-4nqlA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		3 / 3 MET A 373
GLU A 422
ASN A 424
 None
 1.00A 3a27A-4nqlA:
undetectable		 3a27A-4nqlA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		5 / 12 LEU A 269
LEU A 265
ILE A 307
GLN A 310
VAL A 414
 None
None
None
None
EDO  A 505 (-4.1A)
 1.17A 3w1wB-4nqlA:
undetectable		 3w1wB-4nqlA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		4 / 6 GLY A 390
THR A 393
VAL A 410
HIS A 356
 None
None
None
ZN  A 501 (-3.4A)
 1.05A 5ewuA-4nqlA:
undetectable		 5ewuA-4nqlA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		4 / 6 GLY A 390
THR A 393
VAL A 410
HIS A 356
 None
None
None
ZN  A 501 (-3.4A)
 1.10A 5ewuB-4nqlA:
undetectable		 5ewuB-4nqlA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		3 / 3 GLY A 293
LEU A 334
HIS A 304
 None
 0.70A 5u63A-4nqlA:
undetectable		 5u63A-4nqlA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		3 / 3 GLY A 293
LEU A 334
HIS A 304
 None
 0.70A 5u63B-4nqlA:
undetectable		 5u63B-4nqlA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		4 / 5 HIS A 343
ALA A 354
SER A 351
TYR A 411
 None
 1.04A 5yodB-4nqlA:
undetectable		 5yodB-4nqlA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_F_BEZF201_0
(NS3 PROTEASE)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		4 / 5 HIS A 343
ALA A 354
SER A 351
TYR A 411
 None
 1.02A 5yodF-4nqlA:
undetectable		 5yodF-4nqlA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA606_0
(TYROSINASE)		 4nql AMSH-LIKE PROTEASE
SST2
(Schizosaccharomy
ces
pombe) 		4 / 4 HIS A 406
CYH A 397
HIS A 356
HIS A 404
 ZN  A 501 (-3.2A)
ZN  A 501 (-2.2A)
ZN  A 501 (-3.4A)
ZN  A 501 (-3.4A)
 1.31A 5zrdA-4nqlA:
undetectable		 5zrdA-4nqlA:
18.89