SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nqq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 4nqq CADHERIN-3
(Mus
musculus) 		4 / 6 GLY A 144
PRO A 106
LYS A 107
THR A 133
 CA  A 303 ( 4.7A)
None
None
None
 1.24A 2m2oB-4nqqA:
undetectable		 2m2oB-4nqqA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 4nqq CADHERIN-3
(Mus
musculus) 		4 / 6 LEU A  61
GLN A  23
LEU A  60
GLU A  54
 None
 0.99A 3h5gB-4nqqA:
undetectable
3h5gC-4nqqA:
undetectable		 3h5gB-4nqqA:
10.53
3h5gC-4nqqA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4nqq CADHERIN-3
(Mus
musculus) 		4 / 4 LEU A 179
GLY A 178
SER A 177
SER A 176
 None
 1.11A 5uunA-4nqqA:
undetectable		 5uunA-4nqqA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 4nqq CADHERIN-3
(Mus
musculus) 		5 / 12 SER A 116
LEU A 212
ILE A 211
VAL A 174
PHE A 163
 None
 1.33A 5vlmB-4nqqA:
undetectable		 5vlmB-4nqqA:
22.08