SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 232
LEU A 145
ASN A 188
GLU A 246
 None
 0.90A 3zqtA-4nqzA:
undetectable		 3zqtA-4nqzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI
(Pseudomonas
aeruginosa) 		4 / 8 ILE A  90
ILE A  73
LYS A  82
GLY A  81
 None
 0.83A 4hdlA-4nqzA:
undetectable		 4hdlA-4nqzA:
12.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI
(Pseudomonas
aeruginosa) 		4 / 6 GLU A  74
GLY A 142
ASP A  88
ARG A 140
 None
 0.87A 5cdnC-4nqzA:
undetectable
5cdnD-4nqzA:
3.1		 5cdnC-4nqzA:
19.17
5cdnD-4nqzA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI
(Pseudomonas
aeruginosa) 		4 / 6 GLU A  74
GLY A 142
ASP A  88
ARG A 140
 None
 0.88A 5cdnT-4nqzA:
undetectable
5cdnU-4nqzA:
3.1		 5cdnT-4nqzA:
19.17
5cdnU-4nqzA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI
(Pseudomonas
aeruginosa) 		5 / 12 ALA A  21
GLY A 229
MET A  28
GLY A  13
SER A  93
 None
 1.11A 5gwxA-4nqzA:
6.5		 5gwxA-4nqzA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  67
ALA A 123
VAL A  94
LEU A 169
GLY A 172
 None
 1.02A 5igtA-4nqzA:
undetectable		 5igtA-4nqzA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_0
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 4nqz ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE
[NADH] FABI
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 233
GLY A 229
GLY A  23
LEU A 239
PHE A   3
 None
 1.16A 5ybbA-4nqzA:
5.0		 5ybbA-4nqzA:
18.51