SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nrd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 THR A  57
PRO A 208
TYR A  49
 None
 0.97A 2dxrA-4nrdA:
undetectable		 2dxrA-4nrdA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 10 PHE A 104
GLY A 121
ALA A 122
ASP A  31
TYR A  94
 None
 1.41A 2xtkB-4nrdA:
undetectable		 2xtkB-4nrdA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 6 LEU A 171
GLY A  30
LEU A 198
SER A 174
 None
 0.88A 3aiaA-4nrdA:
undetectable		 3aiaA-4nrdA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 8 ASN A  81
ILE A  28
TRP A  66
PHE A 120
 None
 1.45A 3ccfB-4nrdA:
4.2		 3ccfB-4nrdA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9W_A_ACTA506_0
(GTPASE ERA)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		4 / 4 GLU A 218
GLU A  73
ASN A  74
PHE A  70
 None
 1.36A 3r9wA-4nrdA:
4.9		 3r9wA-4nrdA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		5 / 12 LEU A 198
THR A  65
SER A 217
ALA A 122
ASP A  31
 None
 1.27A 3vw1D-4nrdA:
undetectable		 3vw1D-4nrdA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 ASN A 124
TYR A  99
CYH A  90
 None
 1.03A 5lsuB-4nrdA:
undetectable		 5lsuB-4nrdA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4nrd UNCHARACTERIZED
PROTEIN
(Bacteroides
ovatus) 		3 / 3 LEU A 145
ILE A 105
TYR A 191
 None
 0.69A 5uunB-4nrdA:
undetectable		 5uunB-4nrdA:
20.78