SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nrh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4nrh CHAPERONE SYCD
(Chlamydia
pneumoniae) 		4 / 6 PHE B  92
ALA B 110
GLY B 112
TYR B 111
 None
 1.10A 1l7xB-4nrhB:
undetectable		 1l7xB-4nrhB:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 4nrh CHAPERONE SYCD
COPN
(Chlamydia
pneumoniae) 		5 / 10 TYR A 228
ALA A 234
LEU B 157
GLY A 243
PHE A 239
 None
 1.48A 1uhoA-4nrhA:
undetectable		 1uhoA-4nrhA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 4nrh CHAPERONE SYCD
(Chlamydia
pneumoniae) 		5 / 12 LEU B 108
ALA B 107
MET B 100
LEU B 134
PHE B  92
 None
 1.40A 2oaxE-4nrhB:
undetectable		 2oaxE-4nrhB:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 4nrh COPN
(Chlamydia
pneumoniae) 		5 / 12 LEU A 115
GLY A 120
ASP A 127
LEU A 149
LEU A 146
 None
 0.99A 2zbpA-4nrhA:
undetectable		 2zbpA-4nrhA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 6 LYS A 364
GLN A 366
LEU A 368
LEU A 351
 None
 0.91A 3h5gA-4nrhA:
undetectable
3h5gC-4nrhA:
undetectable		 3h5gA-4nrhA:
13.25
3h5gC-4nrhA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 4nrh COPN
(Chlamydia
pneumoniae) 		3 / 3 GLU A 209
GLY A 212
THR A 211
 None
 0.57A 3iazA-4nrhA:
undetectable		 3iazA-4nrhA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_B_SALB900_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 5 VAL A 150
LEU A 149
ILE A 128
ALA A 167
 None
 1.00A 3n8yB-4nrhA:
1.5		 3n8yB-4nrhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 8 ALA A 123
ILE A 119
LEU A 160
ALA A 167
 None
 0.72A 3r9tA-4nrhA:
undetectable		 3r9tA-4nrhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 5 LEU A 112
LEU A 115
LEU A 146
SER A 143
 None
 1.00A 3vhuA-4nrhA:
undetectable		 3vhuA-4nrhA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 4nrh COPN
(Chlamydia
pneumoniae) 		5 / 12 LEU A 149
ALA A  97
ASP A  98
PRO A 154
THR A 153
 None
 1.01A 4njuA-4nrhA:
undetectable		 4njuA-4nrhA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 4nrh COPN
(Chlamydia
pneumoniae) 		5 / 12 LEU A 149
ALA A  97
ASP A  98
PRO A 154
THR A 153
 None
 1.00A 4njuC-4nrhA:
undetectable		 4njuC-4nrhA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 5 SER A 201
GLY A 202
ARG A 204
GLU A 106
 None
 1.33A 4r82A-4nrhA:
undetectable
4r82B-4nrhA:
undetectable		 4r82A-4nrhA:
21.02
4r82B-4nrhA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 4nrh CHAPERONE SYCD
(Chlamydia
pneumoniae) 		3 / 3 ARG B 118
ASP B 119
ARG B 151
 None
 0.51A 4wq4B-4nrhB:
undetectable		 4wq4B-4nrhB:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_B_29SB601_2
(ESTROGEN RECEPTOR)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 5 LEU A 208
MET A 244
LEU A 260
HIS A 215
 None
 1.28A 4xi3B-4nrhA:
2.5		 4xi3B-4nrhA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 5 THR A 275
THR A 267
HIS A 215
LEU A 224
 None
 1.27A 5axaA-4nrhA:
undetectable		 5axaA-4nrhA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 5 THR A 275
THR A 267
HIS A 215
LEU A 224
 None
 1.27A 5axaC-4nrhA:
undetectable		 5axaC-4nrhA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 4nrh COPN
CHAPERONE SYCD
(Chlamydia
pneumoniae;
Chlamydia
pneumoniae) 		3 / 3 HIS B  63
SER B  93
ASN A 197
 None
 0.82A 5cprB-4nrhB:
undetectable		 5cprB-4nrhB:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 4nrh CHAPERONE SYCD
(Chlamydia
pneumoniae) 		4 / 5 TYR B  28
PHE B  86
LEU B  40
PRO B  85
 None
 1.40A 5csyB-4nrhB:
undetectable		 5csyB-4nrhB:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)		 4nrh COPN
CHAPERONE SYCD
(Chlamydia
pneumoniae;
Chlamydia
pneumoniae) 		4 / 7 SER B  51
ILE A 136
GLU A 111
ASN A 104
 None
 1.04A 5n5dA-4nrhB:
undetectable		 5n5dA-4nrhB:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 4nrh COPN
(Chlamydia
pneumoniae) 		4 / 6 SER A 143
HIS A 171
PHE A 175
GLN A 133
 None
 1.47A 5u6nB-4nrhA:
undetectable		 5u6nB-4nrhA:
21.74