SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nso'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 4nso IMMUNITY PROTEIN
(Vibrio
cholerae) 		3 / 3 ASP B  63
LEU B 124
LEU B 123
 None
 0.65A 1ikeA-4nsoB:
undetectable		 1ikeA-4nsoB:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4nso IMMUNITY PROTEIN
(Vibrio
cholerae) 		4 / 8 ASN B  98
LEU B 105
ALA B  47
ARG B  75
 None
 0.98A 3kp6A-4nsoB:
2.2		 3kp6A-4nsoB:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 4nso EFFECTOR PROTEIN
IMMUNITY PROTEIN
(Vibrio
cholerae) 		5 / 10 VAL A 941
LEU A 857
TYR A 851
GLY B  90
GLY B  93
 None
 1.19A 3ls4H-4nsoA:
undetectable		 3ls4H-4nsoA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4nso EFFECTOR PROTEIN
(Vibrio
cholerae) 		4 / 6 ARG A 981
LEU A 982
PHE A 943
LEU A 949
 None
 0.86A 3wg7P-4nsoA:
undetectable
3wg7W-4nsoA:
undetectable		 3wg7P-4nsoA:
20.21
3wg7W-4nsoA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4nso IMMUNITY PROTEIN
(Vibrio
cholerae) 		5 / 12 ASN B  98
LEU B 105
ALA B  47
TYR B  71
ARG B  75
 None
 1.11A 4ejwA-4nsoB:
2.0		 4ejwA-4nsoB:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_B_CLQB303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4nso EFFECTOR PROTEIN
(Vibrio
cholerae) 		5 / 11 GLN A 914
ILE A 950
PHE A 925
GLY A 922
MET A 959
 None
 1.28A 4fglA-4nsoA:
undetectable
4fglB-4nsoA:
undetectable		 4fglA-4nsoA:
20.71
4fglB-4nsoA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 4nso EFFECTOR PROTEIN
IMMUNITY PROTEIN
(Vibrio
cholerae) 		4 / 7 GLY B  89
ILE B  86
GLU B  94
GLN A 914
 None
 1.12A 4g0vA-4nsoB:
undetectable		 4g0vA-4nsoB:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 4nso EFFECTOR PROTEIN
(Vibrio
cholerae) 		3 / 3 TYR A 826
GLN A 972
TRP A 937
 None
 0.98A 4kn2C-4nsoA:
undetectable		 4kn2C-4nsoA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4nso EFFECTOR PROTEIN
(Vibrio
cholerae) 		5 / 12 GLY A 922
MET A 959
GLN A 914
ILE A 950
PHE A 925
 None
 1.14A 4zvmA-4nsoA:
undetectable
4zvmB-4nsoA:
undetectable		 4zvmA-4nsoA:
19.94
4zvmB-4nsoA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 4nso IMMUNITY PROTEIN
(Vibrio
cholerae) 		3 / 3 ASP B 120
SER B  61
TYR B  64
 None
 0.92A 5glmA-4nsoB:
undetectable		 5glmA-4nsoB:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4nso EFFECTOR PROTEIN
(Vibrio
cholerae) 		4 / 5 ARG A 981
LEU A 982
PHE A 943
LEU A 949
 None
 0.89A 5x19C-4nsoA:
undetectable
5x19J-4nsoA:
undetectable		 5x19C-4nsoA:
20.21
5x19J-4nsoA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 4nso EFFECTOR PROTEIN
(Vibrio
cholerae) 		4 / 5 ARG A 981
LEU A 982
PHE A 943
LEU A 949
 None
 0.87A 5x1bP-4nsoA:
undetectable		 5x1bP-4nsoA:
20.21