SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4nss'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECK_A_ILEA601_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4nss	MYCOBACTERIAL PROTEIN (Mycolicibacteriu m smegmatis)	4 / 6	ALA A 94 THR A 95 VAL A 124 VAL A 19	None	0.90A	5eckA-4nssA: undetectable	5eckA-4nssA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECK_D_ILED601_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4nss	MYCOBACTERIAL PROTEIN (Mycolicibacteriu m smegmatis)	4 / 6	ALA A 94 THR A 95 VAL A 124 VAL A 19	None	0.86A	5eckD-4nssA: undetectable	5eckD-4nssA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECL_A_ILEA602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	4nss	MYCOBACTERIAL PROTEIN (Mycolicibacteriu m smegmatis)	4 / 6	ALA A 94 THR A 95 VAL A 124 VAL A 19	None	0.83A	5eclA-4nssA: undetectable	5eclA-4nssA: 12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWW_A_ACAA18_1 (SCRFP-TAG,GP41)	4nss	MYCOBACTERIAL PROTEIN (Mycolicibacteriu m smegmatis)	5 / 12	GLY A 104 SER A 106 LEU A 92 LEU A 97 LEU A 93	None	1.26A	5nwwA-4nssA: undetectable	5nwwA-4nssA: 13.57

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["5ECK_A_ILEA601_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","4nss","MYCOBACTERIAL PROTEIN","Mycolicibacterium smegmatis",4,"ALA A  94;THR A  95;VAL A 124;VAL A  19","None","0.90A","5eckA-4nssA:undetectable","5eckA-4nssA:12.61"],["5ECK_D_ILED601_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","4nss","MYCOBACTERIAL PROTEIN","Mycolicibacterium smegmatis",4,"ALA A  94;THR A  95;VAL A 124;VAL A  19","None","0.86A","5eckD-4nssA:undetectable","5eckD-4nssA:12.61"],["5ECL_A_ILEA602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","4nss","MYCOBACTERIAL PROTEIN","Mycolicibacterium smegmatis",4,"ALA A  94;THR A  95;VAL A 124;VAL A  19","None","0.83A","5eclA-4nssA:undetectable","5eclA-4nssA:12.61"],["5NWW_A_ACAA18_1","SCRFP-TAG,GP41","4nss","MYCOBACTERIAL PROTEIN","Mycolicibacterium smegmatis",5,"GLY A 104;SER A 106;LEU A  92;LEU A  97;LEU A  93","None","1.26A","5nwwA-4nssA:undetectable","5nwwA-4nssA:13.57"]]